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延长自制明胶超声体模的保质期。

Prolonging the Shelf Life of Homemade Gelatin Ultrasound Phantoms.

作者信息

Rathbun Kimberly M, Harryman Claire F, Re Anthony T

机构信息

AU/UGA Medical Partnership, Athens, Georgia, USA.

Department of Emergency Medicine, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.

出版信息

J Med Ultrasound. 2022 May 25;30(2):130-134. doi: 10.4103/JMU.JMU_179_21. eCollection 2022 Apr-Jun.

DOI:10.4103/JMU.JMU_179_21
PMID:35832372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9272711/
Abstract

A significant limitation of homemade phantoms is shelf life. Our goal was to compare the impact on shelf life of easily obtained additives. Fifteen additives were mixed into a gelatin-psyllium hydrophilic mucilloid fiber phantom; three of these additives were used as a layer on top of the phantom. The mixtures were stored in the refrigerator and at room temperature. The samples were evaluated daily for microbial growth and phantom degradation. A 4% of chlorhexidine gluconate layer on top of the phantom quickly made the phantom unusable. The addition of benzoic acid and bleach to the mixture negatively affected phantom appearance with ultrasound imaging. The addition of household bleach or 4% chlorhexidine gluconate to the mixture or a 10% povidone-iodine layer on top of the phantom was the best way to preserve samples stored at room temperature. The refrigerated sample outlasted the paired room temperature sample in every case, with most room temperature samples becoming unusable by day 10 and most refrigerated samples lasting past 50 days.

摘要

自制体模的一个显著局限性是保质期。我们的目标是比较容易获得的添加剂对保质期的影响。将15种添加剂混入明胶-车前草亲水粘胶纤维体模中;其中三种添加剂用作体模顶部的一层。混合物分别储存在冰箱和室温环境中。每天对样品进行微生物生长和体模降解评估。体模顶部4%的葡萄糖酸洗必泰层会迅速使体模无法使用。向混合物中添加苯甲酸和漂白剂会对超声成像下体模的外观产生负面影响。向混合物中添加家用漂白剂或4%的葡萄糖酸洗必泰,或在体模顶部添加10%的聚维酮碘层,是保存室温下储存样品的最佳方法。在每种情况下,冷藏样品的保质期都长于配对的室温样品,大多数室温样品在第10天就无法使用,而大多数冷藏样品的保质期超过50天。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28d/9272711/80b53ce27da5/JMU-30-130-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28d/9272711/76ae8f065a37/JMU-30-130-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28d/9272711/ea7cb7599739/JMU-30-130-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28d/9272711/80b53ce27da5/JMU-30-130-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28d/9272711/76ae8f065a37/JMU-30-130-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28d/9272711/ea7cb7599739/JMU-30-130-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28d/9272711/80b53ce27da5/JMU-30-130-g003.jpg

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Creation of a High-fidelity, Low-cost Pediatric Skull Fracture Ultrasound Phantom.创建一种高保真、低成本的小儿颅骨骨折超声仿真模型。
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A new training model using the self-healing properties of supramolecular hydrogels for endoscopic combined intrarenal surgery.一种利用超分子水凝胶自修复特性的新培训模型,用于内镜下联合肾脏内手术。
Urolithiasis. 2023 Dec 20;52(1):13. doi: 10.1007/s00240-023-01509-4.
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