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使用真实固定器官的新一代超声体模:丹尼体模的诞生。

A New Wave of Ultrasound Phantoms Using Real Fixed Organs: Birth of the Danny Phantom.

作者信息

Fender John M, Habing Amy M, Behbahani Layla K, McCready Sean H

机构信息

College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.

Diagnostic Imaging Department, Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.

出版信息

Vet Radiol Ultrasound. 2025 Sep;66(5):e70078. doi: 10.1111/vru.70078.

DOI:10.1111/vru.70078
PMID:40931509
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12423588/
Abstract

Ultrasonography in veterinary medicine serves a vital role in the diagnosis and management of various medical conditions by allowing noninvasive visualization of internal structures. Veterinary students face many challenges in gaining hands-on experience with ultrasound equipment and developing competencies in ultrasonography. This is largely due to the limited access and ethical dilemmas of live animal models and the high cost of commercial phantoms. To solve these issues, the niche of cost-effective amateur models has exponentially increased. However, while these at-home models solve the financial issues associated with commercial phantoms, they still lack the realism and fidelity necessary to simulate the real-time feedback needed to gain the spatial awareness of this dynamic imaging modality. To foster successful day-one-ready veterinary students, The Ohio State University College of Veterinary Medicine acknowledged that a better solution should be possible. A prospective anatomic study was performed to recognize the imaging anatomy and usability of a new model termed the Danny Phantom. This model was developed by testing various amateur phantom materials from both the literature and self-discovered. These materials were analyzed and deemed satisfactory versus unsatisfactory based on fulfillment of predetermined criteria of an ideal phantom model. It was determined that real fixed organs can be encased in traditional bovine gelatin to produce an ultrasound phantom with recognizable parenchyma. Other additives can be included to give the phantom an imitated peritoneal space and prevent spoilage of the gelatin for an extended period of time.

摘要

超声检查在兽医学中发挥着至关重要的作用,通过对内部结构进行非侵入性可视化,辅助诊断和管理各种病症。兽医专业的学生在获取超声设备的实践经验以及培养超声检查技能方面面临诸多挑战。这主要是由于活体动物模型的获取受限和伦理困境,以及商业仿体的成本高昂。为了解决这些问题,性价比高的自制仿体的市场份额呈指数级增长。然而,虽然这些家用仿体解决了与商业仿体相关的资金问题,但它们仍然缺乏模拟动态成像模式所需的实时反馈以获得空间感知能力所必需的真实感和逼真度。为了培养从第一天起就能胜任工作的兽医学生,俄亥俄州立大学兽医学院认识到应该有可能找到更好的解决方案。开展了一项前瞻性解剖学研究,以识别一种名为“丹尼仿体”的新模型的成像解剖结构和可用性。该模型是通过测试文献中的各种自制仿体材料以及自行发现的材料开发而成的。根据理想仿体模型的预定标准,对这些材料进行分析并判定其是否令人满意。结果表明,真正的固定器官可以包裹在传统的牛明胶中,制成具有可识别实质的超声仿体。还可以添加其他添加剂,使仿体具有模拟的腹膜腔,并防止明胶在较长时间内变质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/df4bc3fde472/VRU-66-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/44c72daaeacb/VRU-66-0-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/35c977503209/VRU-66-0-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/aae87f7df7bd/VRU-66-0-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/58cf07678365/VRU-66-0-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/11526bb42af7/VRU-66-0-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/df4bc3fde472/VRU-66-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/44c72daaeacb/VRU-66-0-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/35c977503209/VRU-66-0-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/aae87f7df7bd/VRU-66-0-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/58cf07678365/VRU-66-0-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/11526bb42af7/VRU-66-0-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a61/12423588/df4bc3fde472/VRU-66-0-g001.jpg

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本文引用的文献

1
Natural ballistic gelatine ultrasound phantoms are suitable to be used for student education and can be produced cheaply and effectively.天然弹道凝胶超声仿体适合用于学生教育,并且可以廉价且有效地生产。
Vet Radiol Ultrasound. 2023 Jul;64(4):733-739. doi: 10.1111/vru.13235. Epub 2023 Apr 10.
2
High-Speed Imaging of Microsphere Transport by Cavitation Activity in a Tissue-Mimicking Phantom.高速成像观察微球在组织模拟体中由空化活动引起的输送
Ultrasound Med Biol. 2023 Jun;49(6):1415-1421. doi: 10.1016/j.ultrasmedbio.2023.01.025. Epub 2023 Mar 15.
3
Using an Ultrasound Tissue Phantom Model for Hybrid Training of Deep Learning Models for Shrapnel Detection.
使用超声组织仿真模型进行用于弹片检测的深度学习模型的混合训练。
J Imaging. 2022 Oct 2;8(10):270. doi: 10.3390/jimaging8100270.
4
Promoting simulation-based training in radiology: a homemade phantom for the practice of ultrasound-guided procedures.推广放射科模拟培训:一种用于超声引导操作实践的自制模体。
Br J Radiol. 2022 Sep 1;95(1137):20220354. doi: 10.1259/bjr.20220354. Epub 2022 Aug 3.
5
Prolonging the Shelf Life of Homemade Gelatin Ultrasound Phantoms.延长自制明胶超声体模的保质期。
J Med Ultrasound. 2022 May 25;30(2):130-134. doi: 10.4103/JMU.JMU_179_21. eCollection 2022 Apr-Jun.
6
Indigenously Developed Ultrasound Phantom Model versus a Commercially Available Training Model: Randomized Double-blinded Study to Assess Its Utility to Teach Ultrasound Guided Vascular Access in a Controlled Setting.自主研发的超声模拟模型与市售训练模型的比较:一项随机双盲研究,旨在评估其在可控环境下教授超声引导血管穿刺的效用。
J Med Ultrasound. 2022 Mar 23;30(1):11-19. doi: 10.4103/JMU.JMU_48_21. eCollection 2022 Jan-Mar.
7
Ultrasonic Attenuation of an Agar, Silicon Dioxide, and Evaporated Milk Gel Phantom.琼脂、二氧化硅和蒸发乳凝胶体模的超声衰减
J Med Ultrasound. 2021 May 31;29(4):239-249. doi: 10.4103/JMU.JMU_145_20. eCollection 2021 Oct-Dec.
8
Alcoholic fixation over formalin fixation: A new, safer option for morphologic and molecular analysis of tissues.酒精固定优于福尔马林固定:一种用于组织形态学和分子分析的新型、更安全的选择。
Saudi J Biol Sci. 2022 Jan;29(1):175-182. doi: 10.1016/j.sjbs.2021.08.075. Epub 2021 Aug 27.
9
Use of gelatin puzzle phantoms to teach medical students isolated ultrasound transducer movements and fundamental concepts.使用明胶拼图模型来教授医学生孤立的超声换能器运动和基本概念。
BMC Med Educ. 2020 Jan 29;20(1):26. doi: 10.1186/s12909-020-1937-8.
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Natural substitutes for formalin: A boon to histopathology!!福尔马林的天然替代品:组织病理学的福音!!
J Oral Maxillofac Pathol. 2018 Jan-Apr;22(1):143. doi: 10.4103/jomfp.JOMFP_53_16.