Coirolo Natalia, Casaravilla Cecilia, Tassino Bettina, Silva Ana
Grupo Cronobiología, Comisión Sectorial de Investigación Científica, Universidad de la República, Jackson 13 01, 11200 Montevideo, Uruguay.
Laboratorio de Inmunología, Instituto de Química Biológica, Facultad de Ciencias, Universidad de la República, Iguá 4225, 11400 Montevideo, Uruguay.
iScience. 2022 Jun 25;25(7):104676. doi: 10.1016/j.isci.2022.104676. eCollection 2022 Jul 15.
The interplay of environmental, social, and behavioral factors influencing human circadian phase in ecological conditions remains elusive. The Uruguayan national dance school END-SODRE operating in two shifts (morning: 8:30-12:30 and night: 20:00-24:00) allowed us to evaluate how social demands, chronotype, environmental light, physical activity, and sleep patterns affected individual circadian phase measured by the onset of the nocturnal increase of melatonin (DLMO) in a single study. The DLMO was 1.5 h earlier in morning-shift dancers (n = 7) compared to night-shift dancers (n = 11). Sleep time and chronotype (only in night-shift dancers) were associated with the circadian phase. In training days, during each participant's phase-advance and phase-delay time windows, light exposure was similar between morning and night-shift dancers and did not correlate with DLMO. In contrast, the time spent in moderate-vigorous physical activity during each participant's phase-lag time window was higher in night-shift dancers than in morning-shift dancers and positively correlated with DLMO.
在生态条件下，影响人类昼夜节律相位的环境、社会和行为因素之间的相互作用仍不明确。乌拉圭国家舞蹈学校END-SODRE分两班授课（上午：8:30 - 12:30和晚上：20:00 - 24:00），这使我们能够在一项研究中评估社会需求、昼夜节律类型、环境光照、身体活动和睡眠模式如何影响通过褪黑素夜间增加开始时间（DLMO）测量的个体昼夜节律相位。与晚班舞者（n = 11）相比，早班舞者（n = 7）的DLMO提前了1.5小时。睡眠时间和昼夜节律类型（仅在晚班舞者中）与昼夜节律相位相关。在训练日，在每个参与者的相位提前和相位延迟时间窗口内，早班和晚班舞者的光照暴露相似，且与DLMO无相关性。相比之下，在每个参与者的相位滞后时间窗口内，晚班舞者进行中等强度到剧烈身体活动的时间比早班舞者更长，且与DLMO呈正相关。
