Tassino Bettina, Silva Ana
Sección Etología, Instituto de Biología, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.
Grupo de Investigación en Cronobiología, Universidad de la República, Montevideo, Uruguay.
Front Physiol. 2024 Mar 7;15:1347377. doi: 10.3389/fphys.2024.1347377. eCollection 2024.
Urban environments, in which ambient light has become a less-reliable entrainer, are challenging for the biological clock to maintain performance. As a consequence, human circadian rhythms are less robust and more variable among individuals. Assessing the individual phase of entrainment, as well as its plastic shifts in response to disturbances of the physical and social environment, is a way to measure circadian disruption. However, this is still difficult to address in real-life scenarios in which several factors modulate the circadian phase not always in a concerted manner. In this perspective, we present the contribution of two real-life situations, in which the circadian system is challenged by important alterations in entraining signals: 1) a trip to the Antarctic summer (socio-environmental challenge), and 2) dancers trained in morning/night shifts (socio-behavioral challenge). Both natural chronobiological experiments are helpful in exploring the functioning and plasticity of the circadian clock and allow for considering individual characteristics and history.
在城市环境中，环境光已成为一种不太可靠的同步信号，这对生物钟维持正常功能构成了挑战。因此，人类的昼夜节律变得不那么稳健，个体之间的差异也更大。评估个体的同步阶段，以及其因物理和社会环境干扰而发生的适应性变化，是衡量昼夜节律紊乱的一种方法。然而，在现实生活场景中，由于多种因素并非总是协同调节昼夜节律相位，因此这一问题仍然难以解决。从这个角度来看，我们介绍了两种现实生活情况的研究成果，在这两种情况中，昼夜节律系统受到同步信号重大变化的挑战：1）南极夏季之行（社会环境挑战），以及2）接受早晚班训练的舞者（社会行为挑战）。这两项自然生物钟实验都有助于探索生物钟的功能和可塑性，并能够考虑个体特征和经历。
