State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, 222 Tianshui Nanlu, Lanzhou 730000, China.
Chem Commun (Camb). 2022 Aug 2;58(62):8710-8713. doi: 10.1039/d2cc03252j.
The unique reactivity of indolyl-substituted -QMs as a new type of two-carbon synthon has been explored for the first time in a novel iron(III)-catalyzed tandem annulation. This (2+2) annulation/retro-4π electrocyclization/imino-Nazarov cyclization cascade reaction is characterized by an unusual structural reconstruction of indolyl-substituted -QMs, leading to an expeditious assembly of synthetically important functionalized cyclopenta[]indoles.
首次在新型铁(III)催化的串联环化反应中探索了吲哚取代的-QM 作为新型二碳合成子的独特反应性。该（2+2）环化/反-4π电环化/亚氨基-Nazarov 环化级联反应的特点是吲哚取代的-QM 发生了不寻常的结构重排，从而快速构建了具有合成重要性的官能化环戊[]吲哚。
