Malmi R, Söderström K O
Int J Androl. 1987 Feb;10(1):157-62. doi: 10.1111/j.1365-2605.1987.tb00177.x.
The distribution of glycoconjugates in germ cells during spermatogenic differentiation, in carcinoma-in-situ (CIS) cells and in seminoma were studied by lectin histochemistry. The results show that human germ cells are rich in carbohydrate-containing compounds with specific alterations in the expression of glucosyl moieties during germ cell development. CIS cells reveal different lectin binding sites from spermatogenic cells, but the distribution of glycosubstances in CIS cells is similar to that of seminoma cells which supports the suggestion of the malignant nature of CIS germ cells.
通过凝集素组织化学研究了生精分化过程中生殖细胞、原位癌（CIS）细胞和精原细胞瘤中糖缀合物的分布。结果表明，人类生殖细胞富含含碳水化合物的化合物，在生殖细胞发育过程中糖基部分的表达有特定变化。CIS细胞显示出与生精细胞不同的凝集素结合位点，但CIS细胞中糖物质的分布与精原细胞瘤细胞相似，这支持了CIS生殖细胞具有恶性性质的观点。
