From the Departments of Diabetes and Endocrinology.
Nuclear Medicine.
Clin Nucl Med. 2022 Sep 1;47(9):e582-e584. doi: 10.1097/RLU.0000000000004332. Epub 2022 Jul 15.
99m Tc-sestamibi thyroid scintigraphy (STS) can aid in differentiating between types 1 and 2 amiodarone-induced thyrotoxicosis (AIT). We present a consecutive case series of 4 men (aged 56-75 years) in whom both 99m Tc-STS and thyroid histology were consistent with a diagnosis of type 2 AIT, representing the first reported histopathologic correlation for this diagnostic test. Median amiodarone treatment duration was 26 months (range, 10-39 months), and amiodarone was discontinued a median of 3 months preoperatively (range, 2-4 months) in all 4 cases. 99m Tc-STS is a promising functional imaging modality, which has the potential to aid clinicians in the diagnostic workup and treatment of AIT.
99mTc- sestamibi 甲状腺闪烁显像（STS）可帮助鉴别 1 型和 2 型胺碘酮诱导的甲状腺功能亢进症（AIT）。我们报告了连续的 4 例男性（年龄 56-75 岁）患者，他们的 99mTc-STS 和甲状腺组织学均符合 2 型 AIT 的诊断，这代表了该诊断检测的首次报道的组织病理学相关性。胺碘酮治疗的中位时间为 26 个月（范围，10-39 个月），4 例患者的中位术前停药时间为 3 个月（范围，2-4 个月）。99mTc-STS 是一种很有前途的功能成像方式，它有可能帮助临床医生进行 AIT 的诊断和治疗。
