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简短综述:胺碘酮相关性甲状腺毒症患者处理方法的新观念。

Short review: novel concepts in the approach to patients with amiodarone-induced thyrotoxicosis.

机构信息

Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Ospedale Cisanello, via Paradisa 2, 56124, Pisa, Italy.

School of Medicine, University of Insubria, Varese, Italy.

出版信息

J Endocrinol Invest. 2024 Feb;47(2):275-283. doi: 10.1007/s40618-023-02168-3. Epub 2023 Sep 20.

DOI:10.1007/s40618-023-02168-3
PMID:37731073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10859339/
Abstract

INTRODUCTION

Amiodarone-induced thyrotoxicosis is associated with high morbidity and mortality rates. The approach to this condition is widely variable across different medical specialists and even among expert endocrinologists. As a matter of fact, the approach to amiodarone-induced thyrotoxicosis has always been considered difficult, due to diagnostic uncertainties easily resulting in missteps, and therapeutic challenges easily resulting in unresponsiveness or slow-responsiveness to the administered drugs.

PURPOSE

Our purpose is to review novelties emerged during the last years about this condition, with the aim to provide novel insights on the diagnostic and therapeutic management of this challenging condition.

摘要

简介

胺碘酮相关性甲状腺毒症与高发病率和死亡率相关。不同医学专家,甚至是专家级内分泌医生,对此病的处理方式也存在很大差异。事实上,由于诊断不确定性很容易导致失误,以及治疗挑战很容易导致药物无反应或反应缓慢,胺碘酮相关性甲状腺毒症的治疗一直被认为是困难的。

目的

我们的目的是回顾近年来关于这种疾病的新进展,旨在为这种具有挑战性的疾病的诊断和治疗管理提供新的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77e/10859339/e294cf91e2d3/40618_2023_2168_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77e/10859339/e294cf91e2d3/40618_2023_2168_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c77e/10859339/e294cf91e2d3/40618_2023_2168_Fig1_HTML.jpg

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Real-life Data on the Effect of Medical Therapy for Amiodarone-induced Thyrotoxicosis on CV Events and Hospitalizations.胺碘酮相关性甲状腺功能亢进症的医学治疗对心血管事件和住院的影响的真实数据。
J Clin Endocrinol Metab. 2023 May 17;108(6):1298-1307. doi: 10.1210/clinem/dgac756.
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J Pers Med. 2023 Oct 30;13(11):1557. doi: 10.3390/jpm13111557.
99mTc-甲氧基异丁基异腈甲状腺显像在胺碘酮诱导的甲状腺功能亢进症中的应用:功能成像-组织病理学相关性。
Clin Nucl Med. 2022 Sep 1;47(9):e582-e584. doi: 10.1097/RLU.0000000000004332. Epub 2022 Jul 15.
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