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职业性接触气球导致的乳胶过敏反应

Latex Anaphylaxis Caused by Occupational Exposure to Balloons.

作者信息

West Robert W, Sharip Akbar

机构信息

Occupational Medicine, Loma Linda University Medical Center, Loma Linda, USA.

出版信息

Cureus. 2022 Jun 12;14(6):e25875. doi: 10.7759/cureus.25875. eCollection 2022 Jun.

DOI:10.7759/cureus.25875
PMID:35836451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9275731/
Abstract

Latex allergies often develop by sensitization to latex allergens by repeated exposure. Because in recent years latex has been ubiquitous in medical equipment, health workers have a higher prevalence of latex allergies than the general population, and care must be taken to ensure workers' safety. We report a case of a female health care worker in her 20s who experienced a severe, biphasic anaphylactic reaction within minutes after being exposed to rubber balloons at a latex-free children's hospital. After being stabilized with epinephrine, dexamethasone, and fluid resuscitation, over a six-hour period, she was discharged home. En route home, her symptoms recurred, and she was admitted to the ICU for observation for impending respiratory failure. She was hospitalized for about 48 hours before being discharged home. She presented to the occupational medicine clinic a few days later for further management. No acute care was required and she was discharged. This case is consistent with occupational latex-induced anaphylaxis. Health personnel should be educated about the importance of compliance with latex allergy mitigation procedures, as well as the severe nature of hypersensitivity reactions that may occur in sensitized persons. It may be beneficial to address the social pressures that can contribute to noncompliance, as balloons are a common gift for children and may be viewed as an acceptable way to cheer up a sick child, tempting some staff to turn a blind eye to policy. The reasons for the policy, and for strict adherence, should be communicated clearly.

摘要

乳胶过敏通常是由于反复接触乳胶过敏原而致敏。近年来,由于乳胶在医疗设备中无处不在,医护人员乳胶过敏的患病率高于普通人群,因此必须注意确保工作人员的安全。我们报告一例20多岁的女性医护人员病例,她在一家无乳胶的儿童医院接触橡胶气球后几分钟内发生了严重的双相过敏反应。在使用肾上腺素、地塞米松和液体复苏使其病情稳定后,经过6个小时,她出院回家。在回家途中,她的症状复发,因即将出现呼吸衰竭而被收入重症监护病房观察。她住院约48小时后出院回家。几天后,她到职业医学诊所接受进一步治疗。无需进行紧急护理,她随后出院。该病例符合职业性乳胶诱发的过敏反应。应教育卫生人员遵守减轻乳胶过敏程序的重要性,以及致敏者可能发生的过敏反应的严重性。解决可能导致不遵守规定的社会压力可能是有益的,因为气球是给孩子的常见礼物,可能被视为让生病的孩子振作起来的一种可接受方式,这会诱使一些工作人员对政策视而不见。应明确传达制定该政策的原因以及严格遵守的原因。

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Latex Anaphylaxis Caused by Occupational Exposure to Balloons.职业性接触气球导致的乳胶过敏反应
Cureus. 2022 Jun 12;14(6):e25875. doi: 10.7759/cureus.25875. eCollection 2022 Jun.
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引用本文的文献

1
Occupational anaphylaxis: A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI).职业性过敏反应:德国过敏与临床免疫学会(DGAKI)立场文件
Allergol Select. 2024 Nov 28;8:407-424. doi: 10.5414/ALX02543E. eCollection 2024.

本文引用的文献

1
Latex Allergy: Where Are We Now and How Did We Get There?乳胶过敏:我们现在在哪里,我们是如何走到这一步的?
J Allergy Clin Immunol Pract. 2017 Sep-Oct;5(5):1212-1216. doi: 10.1016/j.jaip.2017.05.029.
2
Current prevalence rate of latex allergy: Why it remains a problem?目前乳胶过敏的患病率:为何它仍是一个问题?
J Occup Health. 2016 May 25;58(2):138-44. doi: 10.1539/joh.15-0275-RA. Epub 2016 Mar 24.
3
[Latex-free hospitals: benefits and disadvantages].[无乳胶医院:利弊]
Arch Pediatr. 2015 Nov;22(11):1182-7. doi: 10.1016/j.arcped.2015.08.014. Epub 2015 Sep 26.
4
The prevalence of latex sensitisation and allergy and associated risk factors among healthcare workers using hypoallergenic latex gloves at King Edward VIII Hospital, KwaZulu-Natal South Africa: a cross-sectional study.南非夸祖鲁-纳塔尔省爱德华七世国王医院使用低变应原性乳胶手套的医护人员乳胶致敏和过敏的流行情况及其相关危险因素:一项横断面研究。
BMJ Open. 2013 Dec 9;3(12):e002900. doi: 10.1136/bmjopen-2013-002900.