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目前乳胶过敏的患病率:为何它仍是一个问题?

Current prevalence rate of latex allergy: Why it remains a problem?

作者信息

Wu Miaozong, McIntosh James, Liu Jian

机构信息

Center for Diagnostic Nanosystems, Marshall University.

出版信息

J Occup Health. 2016 May 25;58(2):138-44. doi: 10.1539/joh.15-0275-RA. Epub 2016 Mar 24.

Abstract

OBJECTIVES

This article aims to review the current prevalence rate of latex allergy among healthcare workers, susceptible patients, and the general public, and to investigate why latex is still a ubiquitous occupational health hazard.

METHODS

Scientific publications on PubMed, particularly those published within the last five years, and current regulations from agencies such as Food and Drug Administration (FDA) were reviewed. Consumer and commercial products that may contain latex were also surveyed.

RESULTS

Approximately 12 million tons of natural rubber latex is produced annually and is widely used to manufacture millions of consumer and commercial products. Only limited number of latex-derived products have been approved and regulated by government agencies, such as FDA, whereas the majority of finished products do not label whether they contain latex. Owing to millions of unidentifiable products containing latex and many routes for exposure to latex, preventing contact with latex allergens and reducing the prevalence of latex allergy are more difficult than expected. Reported data suggest that the average prevalence of latex allergy worldwide remains 9.7%, 7.2%, and 4.3% among healthcare workers, susceptible patients, and general population, respectively.

CONCLUSIONS

Latex-derived products are ubiquitous, and latex allergy remains a highly prevalent health risk in many occupations and to the general population. Developing alternative materials and increasing the ability to identify and label latex-derived products will be practicable approaches to effectively control the health risks associated with latex.

摘要

目的

本文旨在综述医护人员、易感患者及普通公众中乳胶过敏的当前患病率,并探究为何乳胶仍是一种普遍存在的职业健康危害。

方法

查阅了PubMed上的科学出版物,特别是过去五年内发表的文献,以及食品药品监督管理局(FDA)等机构的现行法规。还对可能含有乳胶的消费产品和商业产品进行了调查。

结果

每年生产约1200万吨天然橡胶乳胶,广泛用于制造数百万种消费产品和商业产品。只有有限数量的乳胶衍生产品得到了FDA等政府机构的批准和监管,而大多数成品并未标明是否含有乳胶。由于数百万种无法识别的含乳胶产品以及许多接触乳胶的途径,防止接触乳胶过敏原和降低乳胶过敏患病率比预期更困难。报告数据表明,全球医护人员、易感患者和普通人群中乳胶过敏的平均患病率分别仍为9.7%、7.2%和4.3%。

结论

乳胶衍生产品无处不在,乳胶过敏在许多职业和普通人群中仍然是一种高度普遍的健康风险。开发替代材料以及提高识别和标注乳胶衍生产品的能力将是有效控制与乳胶相关健康风险的可行方法。

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