Pattnaik Lipipuspa, Naaz Shaik A, Das Banya, Dash Putul, Pattanaik Manasi
Obstetrics and Gynecology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Cureus. 2022 Jun 9;14(6):e25790. doi: 10.7759/cureus.25790. eCollection 2022 Jun.
Introduction A paucity of data exists regarding pregnancy outcome data in women with polycystic ovarian syndrome (PCOS). Therefore, we conducted this study to compare the pregnancy outcomes of women with and without in Indian population. Materials and methods A total of 102 antenatal pregnant women aged between 18 and 45 years were included in this study conducted at the Department of Obstetrics and Gynecology, Pradyumna Bal Memorial Hospital, Kalinga Institute of Medical Sciences, Bhubaneswar, India. Fifty-one women had PCOS, and 51 women served as controls. We recorded patient demographic, clinical, menstrual, and pregnancy data for each group. All participants were monitored until delivery, and we recorded maternal outcomes, including spontaneous abortion, preterm birth, gestational diabetes mellitus (GDM), and pregnancy-induced hypertension (PIH). We used IBM SPSS Statistics version 20.0 for Windows (Armonk, NY: IBM Corp.) for statistical analysis and the chi-square test to analyze relationships in categorical variables. Results Most participants were aged between 20 and 30 years (64.7%). A high body mass index (BMI) was twice as common in women with PCOS than the control group. Most women with PCOS with pregnancy complications were overweight (62.7%) with a BMI of 25 to 29.9 kg/m. A majority of women in the PCOS group (86.3%) required reproductive technology assistance, while none in the control group needed the same type of assistance. In the PCOS group, spontaneous abortions (SAB) occurred in 5.9%, GDM occurred in 17.6%, PIH in 21.6%, and preterm births in 33.3%. By contrast, the control group saw SAB occur in only 3.9%, GDM occurred in 9.8%, PIH was identical in 21.6%, and preterm births occurred in 17.6% of women without PCOS. Cesarian delivery occurred in 64.7% of women with PCOS, while only 39.2% of women without PCOS had cesarian delivery was statistically not significant. Conclusion We conducted this study to assess the impact of PCOS on pregnancy against pregnant women without PCOS. Pregnant women with PCOS were more likely to experience complications such as SAB, GDM, and preterm birth than pregnant women without PCOS. Therefore, pregnancies in women with PCOS are high-risk pregnancies that require frequent and timely antenatal care.
关于多囊卵巢综合征（PCOS）女性的妊娠结局数据匮乏。因此，我们开展了本研究，以比较印度人群中患有和未患有PCOS的女性的妊娠结局。
本研究纳入了印度布巴内斯瓦尔卡林加医学科学研究所普拉迪尤马纳·巴尔纪念医院妇产科的102名年龄在18至45岁之间的产前孕妇。51名女性患有PCOS，51名女性作为对照。我们记录了每组患者的人口统计学、临床、月经和妊娠数据。对所有参与者进行监测直至分娩，并记录孕产妇结局，包括自然流产、早产、妊娠期糖尿病（GDM）和妊娠高血压综合征（PIH）。我们使用适用于Windows的IBM SPSS Statistics 20.0版（纽约州阿蒙克：IBM公司）进行统计分析，并使用卡方检验分析分类变量之间的关系。
大多数参与者年龄在20至30岁之间（64.7%）。患有PCOS的女性中高体重指数（BMI）的发生率是对照组的两倍。大多数患有妊娠并发症的PCOS女性超重（62.7%），BMI为25至29.9kg/m。PCOS组中的大多数女性（86.3%）需要生殖技术辅助，而对照组中无人需要此类辅助。在PCOS组中，自然流产（SAB）发生率为5.9%，GDM发生率为17.6%，PIH发生率为21.6%，早产发生率为33.3%。相比之下，对照组中SAB发生率仅为3.9%，GDM发生率为9.8%，PIH发生率相同为21.6%，未患PCOS的女性中早产发生率为17.6%。患有PCOS的女性中有64.7%进行了剖宫产，而未患PCOS的女性中只有39.2%进行了剖宫产，差异无统计学意义。
我们开展本研究以评估PCOS对妊娠的影响，并与未患PCOS的孕妇进行对比。患有PCOS的孕妇比未患PCOS的孕妇更易出现SAB、GDM和早产等并发症。因此，患有PCOS的女性妊娠属于高危妊娠，需要频繁且及时的产前护理。
