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Clonal hematopoiesis is not significantly associated with COVID-19 disease severity.

作者信息

Zhou Yifan, Shalhoub Ruba, Rogers Stephanie N, Yu Shiqin, Gu Muxin, Fabre Margarete A, Quiros Pedro M, Shin Tae-Hoon, Diangson Arch, Deng Wenhan, Anand Shubha, Lu Wenhua, Cullen Matthew, Godfrey Anna L, Preller Jacobus, Hadjadj Jerome, Jouanguy Emmanuelle, Cobat Aurélie, Abel Laurent, Rieux-Laucat Frederic, Terrier Benjamin, Fischer Alain, Novik Lara, Gordon Ingelise J, Strom Larisa, Gaudinski Martin R, Lisco Andrea, Sereti Irini, Gniadek Thomas J, Biondi Andrea, Bonfanti Paolo, Imberti Luisa, Dalgard Clifton L, Zhang Yu, Dobbs Kerry, Su Helen C, Notarangelo Luigi D, Wu Colin O, Openshaw Peter J M, Semple Malcolm G, Mallat Ziad, Baillie Kenneth, Dunbar Cynthia E, Vassiliou George S

机构信息

Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.

Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health (NIH), Bethesda, MD.

出版信息

Blood. 2022 Oct 6;140(14):1650-1655. doi: 10.1182/blood.2022015721.

DOI:10.1182/blood.2022015721
PMID:35839449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9293387/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bd/9750849/485ff92945a9/BLOOD_BLD-2022-015721-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bd/9750849/485ff92945a9/BLOOD_BLD-2022-015721-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bd/9750849/485ff92945a9/BLOOD_BLD-2022-015721-gr1.jpg

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本文引用的文献

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2
Clonal hematopoiesis is associated with risk of severe Covid-19.克隆性造血与严重 COVID-19 风险相关。
Nat Commun. 2021 Oct 13;12(1):5975. doi: 10.1038/s41467-021-26138-6.
3
Mapping the human genetic architecture of COVID-19.绘制人类 COVID-19 遗传结构图谱。
单细胞多组学揭示DNMT3A和TET2突变克隆性造血在炎症反应中的不同作用。
Blood Adv. 2025 Jan 28;9(2):402-416. doi: 10.1182/bloodadvances.2024014467.
4
Clonal hematopoiesis of indeterminate potential as a prognostic factor: a systematic review and meta-analysis.克隆性造血不定潜能作为预后因素：系统评价和荟萃分析。
Blood Adv. 2024 Jul 23;8(14):3771-3784. doi: 10.1182/bloodadvances.2024013228.
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Clonal hematopoiesis in people with advanced HIV and associated inflammatory syndromes.患有晚期 HIV 且伴有炎症综合征人群中的克隆性造血。
JCI Insight. 2024 Apr 2;9(9):e174783. doi: 10.1172/jci.insight.174783.
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