State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Retina. 2022 Nov 1;42(11):2051-2058. doi: 10.1097/IAE.0000000000003568.
To investigate the outcomes of macular buckling combined with vitrectomy and inverted internal limiting membrane flap technique for highly myopic full-thickness macular hole (FTMH) with macular retinoschisis.
Twenty-six eyes of 26 consecutive patients were retrospectively included. Twelve eyes underwent macular buckling alone (buckling group). Fourteen eyes underwent macular buckling and vitrectomy with an inverted internal limiting membrane flap technique (combination group). Patients were followed for at least 9 months. Rates of FTMH closure and macular retinoschisis resolution, best-corrected visual acuity gained at the final visit were evaluated.
The mean follow-up time was 13.00 ± 3.16 months. FTMH closed in six eyes (50%) of the buckling group and 13 eyes (92.86%) of the combination group ( P = 0.026) at the final visit. The macular retinoschisis resolution rate was close between two groups (100% vs. 92.86%; P = 1.000). Both groups achieved significant improvement in best-corrected visual acuity (10.42 ± 17.25 and 16.36 ± 10.39 Early Treatment Diabetic Retinopathy Study letters; P = 0.014 and P < 0.001). The combination group achieved slightly more best-corrected visual acuity improvement, but the difference fell short of significance ( P =0.312).
Combination of macular buckling and vitrectomy with the inverted internal limiting membrane flap technique could achieve a high FTMH closure rate and significant best-corrected visual acuity improvement in FTMH with macular retinoschisis.
研究黄斑兜带术联合玻璃体切除术和内界膜翻转瓣技术治疗伴有黄斑视网膜劈裂的高度近视全层黄斑孔(FTMH)的疗效。
回顾性纳入 26 例(26 只眼)连续患者。12 只眼行单纯黄斑兜带术(兜带组),14 只眼行黄斑兜带术联合玻璃体切除术和内界膜翻转瓣技术(联合组)。所有患者均随访至少 9 个月。评估最终随访时 FTMH 闭合率和黄斑视网膜劈裂复位率以及最佳矫正视力的提高情况。
平均随访时间为 13.00 ± 3.16 个月。最终随访时,兜带组 6 只眼(50%)和联合组 13 只眼(92.86%)的 FTMH 闭合(P = 0.026)。两组的黄斑视网膜劈裂复位率接近(100%比 92.86%;P = 1.000)。两组的最佳矫正视力均显著提高(10.42 ± 17.25 和 16.36 ± 10.39 ETDRS 字母;P = 0.014 和 P < 0.001)。联合组的最佳矫正视力提高略多,但差异无统计学意义(P = 0.312)。
黄斑兜带术联合玻璃体切除术和内界膜翻转瓣技术可提高伴有黄斑视网膜劈裂的 FTMH 闭合率,并显著提高 FTMH 的最佳矫正视力。