State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Sun Yat-sen University, Guangzhou, 510060, China.
Eye (Lond). 2023 Sep;37(13):2730-2735. doi: 10.1038/s41433-023-02406-1. Epub 2023 Jan 31.
To compare the efficacy of macular buckling (MB) alone against a combined internal limiting membrane (ILM) inversion flap for full-thickness macular hole (FTMH)-associated macular detachment (MD) in patients with high myopia.
This was a prospective interventional case series of patients with high myopia surgically treated with MB alone or combined with an inverted ILM flap for FTMH- associated MD. Best-corrected visual acuity (BCVA) at the 24-month postoperative follow-up, rate of initial retinal reattachment and macular hole closure were measured.
A total of 62 eyes from 62 participants (33 in the MB group, 29 in the combination group) were studied. Postoperative BCVA improved significantly in both the combination group (P < 0.001) and the MB group (P = 0.027). The postoperative BCVA at 12 months (P = 0.021) and 24 months (P = 0.041) was significantly better in the combination group than in the MB group. The postoperative BCVA was not significantly different between the eyes with closed and unclosed MH at each follow-up time point (P > 0.05). In the combination group, we observed earlier retinal reattachment and closure of the MH as well as a higher rate of MH closure (82.8% vs. 66.7%) than in the MB group, although this difference was insignificant (P = 0.248).
MB combined with the ILM flap inversion technique achieved better postoperative BCVA and a higher success rate of MH closure than MB alone. We believe that combination surgery should be preferentially recommended.
比较单纯黄斑兜带术(MB)与内界膜翻转瓣联合治疗高度近视全层黄斑裂孔(FTMH)相关黄斑脱离(MD)的疗效。
这是一项前瞻性的干预性病例系列研究,纳入了接受单纯 MB 或 MB 联合内界膜翻转瓣治疗 FTMH 相关 MD 的高度近视患者。在术后 24 个月随访时,测量最佳矫正视力(BCVA)、初始视网膜复位率和黄斑裂孔闭合率。
共纳入 62 只眼(62 例患者),其中 33 只眼接受 MB 治疗,29 只眼接受联合治疗。两组术后 BCVA 均显著提高(组合组:P<0.001;MB 组:P=0.027)。联合组术后 12 个月(P=0.021)和 24 个月(P=0.041)的 BCVA 明显优于 MB 组。在每个随访时间点,闭合和未闭合 MH 的眼术后 BCVA 无显著差异(P>0.05)。联合组视网膜更早复位,MH 更早闭合,MH 闭合率更高(82.8%比 66.7%),但差异无统计学意义(P=0.248)。
MB 联合内界膜翻转瓣技术可提高术后 BCVA,增加 MH 闭合率,优于单纯 MB 治疗。我们认为,联合手术应优先推荐。