Degener J E, Naidoo J L, Noble W C, Phillips I, Marples R R
J Antimicrob Chemother. 1987 Apr;19(4):505-12. doi: 10.1093/jac/19.4.505.
Gentamicin-resistant coagulase-negative staphylococci were found on various sites of the skin of 20 of 27 patients on continuous ambulatory peritoneal dialysis (CAPD). In 12 cases isolates with identical susceptibility patterns could be recovered from the same patients at intervals of 2-8 weeks. In seven of these cases isolates from individuals repeatedly had the same phage type, biotype and plasmid profile and three patients shared such identical strains. The use of plasmid profiles proved to be most satisfactory for epidemiological purposes. It was concluded that out-patients on CAPD may persistently harbour their own gentamicin-resistant coagulase-negative staphylococcal strain and that cross-colonization may also occur.
在27例持续性非卧床腹膜透析(CAPD)患者中,有20例患者的皮肤不同部位发现了耐庆大霉素的凝固酶阴性葡萄球菌。在12例患者中,每隔2 - 8周可从同一患者身上分离出药敏模式相同的菌株。其中7例患者反复分离出的菌株具有相同的噬菌体类型、生物型和质粒图谱,3例患者共享相同菌株。结果表明,利用质粒图谱进行流行病学研究最为理想。得出的结论是,CAPD门诊患者可能持续携带自身耐庆大霉素的凝固酶阴性葡萄球菌菌株,并且可能发生交叉定植。