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身体活动强度对中年及以上中国成年人认知功能和抑郁症状纵向轨迹的影响:一项 8 年前瞻性研究。

Impact of physical activity intensity on longitudinal trajectories of cognitive function and depressive symptoms in middle-aged and older Chinese adults: Eight-year prospective study.

机构信息

Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong SAR, China.

School of Nursing, The University of Hong Kong, Hong Kong SAR, China.

出版信息

J Affect Disord. 2022 Oct 15;315:64-69. doi: 10.1016/j.jad.2022.07.012. Epub 2022 Jul 12.

Abstract

BACKGROUND

Little is known about how longitudinal trajectories of cognitive function and depressive symptoms are impacted by varying levels of physical activity (PA) intensity.

METHOD

The data were from the China Health and Retirement Longitudinal Study, a nationally representative household study of the Chinese population aged 45 years and older. The sample included 5025 middle-aged and older adults (mean age = 57) who self-reported their cognitive function, depressive symptoms, and PA intensity (vigorous PA, moderate PA, and light PA) every two years from 2011 to 2018.

RESULT

On average, every 2 years, cognitive function decreased by 0.17 points (95 % CI: [-0.22, -0.12], P < 0.05), while depressive symptoms increased by 0.23 points (95 % CI: [0.19,0.27], P < 0.001). Middle-aged and older adults who reported a minimum of 6 days/week frequency of moderate PA (β = 0.14, 95 % CI:[0.01,0.27]) had lower reduction of cognitive function compared to people with none moderate PA but not vigorous PA (β = 0.04, 95 % CI:[-0.11,0.19]) and light PA (β = 0.06, 95 % CI:[-0.09,0.22]). The increase in depressive symptoms was significantly slower among middle-aged and older adults with a minimum of 6 days/week light PA (β = -0.02, 95 % CI:[-0.03,-0.002]).

CONCLUSION

A minimum of 6 days of moderate PA a week was associated with a slower reduction in cognitive function and a minimum of 6 days of light PA a week was linked to a delayed increase in depressive symptoms. In middle-aged and older adults, a tailored PA intensity may be more beneficial in achieving the maximum improvement in cognitive function and mental health.

摘要

背景

对于体力活动(PA)强度不同如何影响认知功能和抑郁症状的纵向轨迹,目前知之甚少。

方法

数据来自中国健康与退休纵向研究,这是一项对中国 45 岁及以上人群的全国代表性家庭研究。该样本包括 5025 名中老年成年人(平均年龄=57 岁),他们从 2011 年到 2018 年每两年报告一次认知功能、抑郁症状和 PA 强度(剧烈 PA、中度 PA 和轻度 PA)。

结果

平均而言,每两年,认知功能下降 0.17 分(95%CI:[-0.22,-0.12],P<0.05),而抑郁症状增加 0.23 分(95%CI:[0.19,0.27],P<0.001)。与没有中度 PA 的人相比,报告每周至少 6 天有规律的中度 PA(β=0.14,95%CI:[0.01,0.27])的中老年成年人认知功能下降幅度较低,但与没有剧烈 PA(β=0.04,95%CI:[-0.11,0.19])和轻度 PA(β=0.06,95%CI:[-0.09,0.22])的人相比没有差异。每周至少 6 天有规律的轻度 PA 的中老年成年人抑郁症状的增加速度明显较慢(β=-0.02,95%CI:[-0.03,-0.002])。

结论

每周至少 6 天进行中度 PA 与认知功能下降速度较慢有关,每周至少 6 天进行轻度 PA 与抑郁症状增加速度较慢有关。在中老年成年人中,量身定制的 PA 强度可能更有利于最大限度地提高认知功能和心理健康。

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