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腐胺和尸胺是产碱韦荣球菌和小韦荣球菌中肽聚糖的组成成分。

Putrescine and cadaverine are constituents of peptidoglycan in Veillonella alcalescens and Veillonella parvula.

作者信息

Kamio Y, Nakamura K

出版信息

J Bacteriol. 1987 Jun;169(6):2881-4. doi: 10.1128/jb.169.6.2881-2884.1987.

DOI:10.1128/jb.169.6.2881-2884.1987
PMID:3584075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC212205/
Abstract

Veillonella alcalescens ATCC 17745, a strictly anaerobic, gram-negative small coccus, requires putrescine or cadaverine for growth (M. B. Ritchey, and E. A. Delwiche, J. Bacteriol. 124:1213-1219, 1975). Both putrescine and cadaverine were demonstrated to be incorporated exclusively into the peptidoglycan layer of V. alcalescens ATCC 17745. V. parvula GAI 0574 also proved to contain putrescine as a component of peptidoglycan. The primary chemical structure of the peptidoglycan common to the two Veillonella species is N-acetylglucosamine-N-acetylmuramic acid-L-alanine-D-glutamic acid gamma-meso-diaminopimelic acid-D-alanine. Putrescine or cadaverine links covalently to the alpha-carboxyl group of the D-glutamic acid residue of the peptidoglycan is necessary for normal cell growth. In V. alcalescens ATCC 17745, above 40% saturation at cadaverine linked to the alpha-carboxyl group of the D-glutamic acid residue of the peptidoglycan is necessary for normal growth.

摘要

产碱韦荣球菌ATCC 17745是一种严格厌氧的革兰氏阴性小球菌,生长需要腐胺或尸胺(M. B. 里奇和E. A. 德尔维奇,《细菌学杂志》124:1213 - 1219,1975年)。已证明腐胺和尸胺都仅被整合到产碱韦荣球菌ATCC 17745的肽聚糖层中。小韦荣球菌GAI 0574也被证明含有腐胺作为肽聚糖的组成成分。这两种韦荣球菌共有的肽聚糖的主要化学结构是N - 乙酰葡糖胺 - N - 乙酰胞壁酸 - L - 丙氨酸 - D - 谷氨酸 - γ - 内消旋二氨基庚二酸 - D - 丙氨酸。腐胺或尸胺与肽聚糖中D - 谷氨酸残基的α - 羧基共价连接对于正常细胞生长是必需的。在产碱韦荣球菌ATCC 17745中,肽聚糖中与D - 谷氨酸残基的α - 羧基相连的尸胺饱和度高于40%对于正常生长是必需的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b708/212205/fdefa1dd9516/jbacter00196-0571-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b708/212205/fdfd0ab2a37c/jbacter00196-0570-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b708/212205/fdefa1dd9516/jbacter00196-0571-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b708/212205/fdfd0ab2a37c/jbacter00196-0570-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b708/212205/fdefa1dd9516/jbacter00196-0571-a.jpg

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