Department of Plastic Surgery, The First Affiliated Hospital of Jinan University, Huangpu West Road 613, Guangdong Province, 510630, Guangzhou, People's Republic of China.
Innovative Technology Research Institute of Tissue Repair and Regeneration, Key Laboratory of Regenerative Medicine, Ministry of Education, Huangpu West Road 613, Guangdong Province, 510630, Guangzhou, People's Republic of China.
BMC Infect Dis. 2022 Jul 15;22(1):617. doi: 10.1186/s12879-022-07574-1.
Liposuction has become one of the most popular cosmetic surgeries in China. However, few studies have discussed infectious shock caused by C. perfringens as one of the causes of death after liposuction.
A 24-year-old woman was brought to the emergency department (ED) of Guangzhou Chinese Overseas Hospital for treatment. The patient had undergone liposuction in her bilateral lower limbs two days prior. At the ED, the patient was unconscious, and had bilateral equal-sized (diameter, 6 mm) round pupils, no light reflex, a blood pressure (BP) of 71/33 mmHg, a heart rate of 133 bpm, and an SpO2 of 70%. She had bilateral limb swelling, extensive ecchymoses in her lower abdomen and bilateral thighs, local crepitus, blisters, weak pulses on her femoral artery and dorsalis pedis, high skin tension, and hemoglobin of 32 g/L. The patient was diagnosed with Clostridium perfringens infection, and she underwent debridement surgery and supportive treatment. But the patient's BP could not improve. At 8:28 pm on the day of admission, the patient was declared clinically dead after the electrocardiograph showed a horizontal line and spontaneous respiration ceased.
Failure to meet surgical disinfection and environmental standards may be the cause of infection of C. perfringens through wounds. Therefore, it is necessary to strengthen the environmental disinfection of the operating room, and standardize the sterile conditions of the operation staff and patients before and during operation. Liposuction surgery necrotizing fasciitis is a rare but fatal complications, especially if diagnosis delay, therefore it is critical for early diagnosis and treatment of gas gangrene.
吸脂术已成为中国最受欢迎的美容手术之一。然而，很少有研究探讨梭状芽孢杆菌引起的感染性休克是吸脂术后死亡的原因之一。
一名 24 岁女性因双侧下肢吸脂术后两天被送往广州华侨医院急诊科（ED）就诊。就诊时，患者处于昏迷状态，双侧瞳孔等大（直径 6mm），对光反射消失，血压（BP）71/33mmHg，心率 133bpm，SpO2 为 70%。她的双侧肢体肿胀，下腹部和双侧大腿广泛瘀斑，局部有捻发音、水疱、股动脉和足背动脉搏动减弱，皮肤张力高，血红蛋白 32g/L。患者被诊断为梭状芽孢杆菌感染，并接受了清创手术和支持性治疗。但患者的血压无法改善。入院当天晚上 8 点 28 分，心电图显示直线，自主呼吸停止，患者被宣布临床死亡。
未能达到手术消毒和环境标准可能是通过伤口感染梭状芽孢杆菌的原因。因此，有必要加强手术室的环境消毒，并规范手术人员和患者在手术前后的无菌条件。吸脂术后坏死性筋膜炎是一种罕见但致命的并发症，特别是如果诊断延迟，因此早期诊断和治疗气性坏疽至关重要。
