Smith M A, Jones E A, Strachan R K, Nicoll J J, Best J J, Tothill P, Hughes S P
J Bone Joint Surg Br. 1987 May;69(3):441-7. doi: 10.1302/0301-620X.69B3.3584200.
The uptake of 99mTc-MDP was studied in 73 patients after a tibial fracture. The image obtained five minutes after injection during a period between one and four weeks after fracture was found to be related to the incidence of non-union after six months. A ratio of 1.3 between the uptake at the fracture site and at normal bone adjacent to it predicted non-union in an individual patient with a sensitivity of about 70% and a specificity of 90%.
对73例胫骨骨折患者的99mTc-MDP摄取情况进行了研究。发现在骨折后1至4周期间注射后5分钟获得的图像与6个月后骨不连的发生率相关。骨折部位与相邻正常骨的摄取比值为1.3时，预测个体患者骨不连的敏感性约为70%，特异性为90%。
