van As A, McDonald I, Gebhardt T, Dowdeswell R
S Afr Med J. 1978 Jun 17;53(25):1011-5.
Carbuterol tablets (2,0 mg) were compared with the tablets of fenoterol (2,5 mg) and hexoprenaline (1 mg). The three drugs were shown to be equally effective for a period of 4 hours, but carbuterol and fenoterol exerted a statistically significant bronchodilating action for 7 and 8 hours respectively, while the action of hexoprenaline lasted for 4 hours in the majority of patients. The aerosols of carbuterol (200 mg) and fenoterol (400 mg) appeared to be similar in inhibiting exercise-induced asthma, whereas hexoprenaline (200 mg) did not appear to be as effective.
将克仑特罗片(2.0毫克)与非诺特罗片(2.5毫克)和己双肾上腺素片(1毫克)进行了比较。结果表明,这三种药物在4小时内疗效相当,但克仑特罗和非诺特罗分别在7小时和8小时产生了具有统计学意义的支气管扩张作用,而在大多数患者中,己双肾上腺素的作用持续4小时。克仑特罗气雾剂(200毫克)和非诺特罗气雾剂(400毫克)在抑制运动诱发哮喘方面似乎相似,而己双肾上腺素气雾剂(200毫克)似乎效果不佳。