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雄激素的环境归宿和毒性:一项批判性回顾。

Environmental fate and toxicity of androgens: A critical review.

机构信息

School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen, 518055, China; Environmental Engineering Research Centre, Department of Civil Engineering, The University of Hong Kong, China.

School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen, 518055, China.

出版信息

Environ Res. 2022 Nov;214(Pt 2):113849. doi: 10.1016/j.envres.2022.113849. Epub 2022 Jul 16.

DOI:10.1016/j.envres.2022.113849
PMID:35843282
Abstract

Androgens are released by humans and livestock into the environment and which cause potent endocrine disruptions even at nanogram per liter levels. In this article, we reviewed updated research results on the structure, source, distribution characteristics and the fate of androgens in ecological systems; and emphasized the potential risk of androgens in aquatic organism. Androgens have moderately solubility in water (23.6-58.4 mg/L) and moderately hydrophobic (log Kow 2.75-4.40). The concentration of androgens in surface waters were mostly in ng/L ranges. The removal efficiencies of main wastewater treatment processes were about 70-100%, except oxidation ditch and stabilization ponds. Sludge adsorption and microbial degradation play important role in the androgens remove. The conjugated androgens were transformed into free androgens in environmental matrices. Global efforts to provide more toxicity data and establish standard monitoring methods need a revisit. Of the day available, there is an urgent need for comprehensive consideration of the impact of androgens on the environment and ecology.

摘要

雄激素由人类和牲畜释放到环境中,即使在纳克/升水平也会引起强烈的内分泌干扰。本文综述了雄激素在生态系统中的结构、来源、分布特征和命运的最新研究结果;并强调了雄激素对水生生物的潜在风险。雄激素在水中的溶解度适中(23.6-58.4mg/L),疏水性适中(log Kow 2.75-4.40)。地表水中雄激素的浓度大多在纳克/升范围内。主要废水处理工艺的去除效率约为 70-100%,氧化沟和稳定塘除外。污泥吸附和微生物降解在雄激素去除中起重要作用。共轭雄激素在环境基质中转化为游离雄激素。全球需要努力提供更多的毒性数据并建立标准监测方法。在现有的数据中,迫切需要全面考虑雄激素对环境和生态的影响。

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