The current state of interferon assays permits the performance of a moderate number of determinations within 20 to 24 hours. A few procedures permit a small number of assays to be made within 8-10 hours. The decision to routinely use a specific procedure must be based on a careful evaluation of many factors in addition to the need for rapid results. In genral, it is assumed that preference would be given to a 16 hour determination requiring 2 hours of actual technical time, as compared to an 8 hour determination requiring 6 hours of technical time.