Division 1 Department of Neurology, Nanping First Hospital, Nanping, 353000 Fujian Province, China.
Comput Math Methods Med. 2022 Jul 6;2022:6350033. doi: 10.1155/2022/6350033. eCollection 2022.
This study was aimed at exploring the feasibility and clinical efficacy of nerve interventional thrombectomy (NIT) to treat occlusion of cranial artery M1 and M2 segments. 80 patients were selected and rolled into a control group (intravenous thrombolysis) and an experimental group (NIT). Patients' vascular recanalization rates following therapy were compared, and the National Institutes of Health Stroke Scale (NIHSS) was used to measure neurological function. The improvement in hemodynamics and the occurrence of adverse responses were compared. The results showed that the experimental group's recanalization rate was up to 74.23%, which was significantly greater than the control group's ( < 0.05). One week after treatment, the neurological function scores in both groups decreased, and the score in the experimental group was only 15.23, which was much lower than that in the control group ( < 0.05). The peak systolic flow rates of the basilar artery, internal carotid artery, and common carotid artery in the experimental group were 132 cm/s, 147 cm/s, and 114 cm/s, respectively, which were lower greatly than those in the control group ( < 0.05). There was no significant difference in incidence of adverse reactions between the two groups ( > 0.05). In summary, NIT showed a significant therapeutic effect on cranial artery occlusion of M1 and M2 segments, can dredge the occluded blood vessels, and effectively improve the neurological deficits of patients, showing reliable feasibility.
本研究旨在探讨神经介入取栓术(NIT)治疗颅动脉 M1 和 M2 段闭塞的可行性和临床疗效。选择 80 例患者分为对照组(静脉溶栓)和实验组(NIT)。比较两组患者治疗后的血管再通率,采用国立卫生研究院卒中量表(NIHSS)评估神经功能。比较两组患者的血液动力学改善情况和不良反应发生情况。结果显示,实验组的再通率高达 74.23%,明显高于对照组(<0.05)。治疗后 1 周,两组患者的神经功能评分均降低,实验组评分为 15.23,明显低于对照组(<0.05)。实验组患者基底动脉、颈内动脉和颈总动脉的收缩期峰值血流速度分别为 132cm/s、147cm/s 和 114cm/s,均明显低于对照组(<0.05)。两组不良反应发生率差异无统计学意义(>0.05)。综上所述,NIT 对 M1 和 M2 段颅动脉闭塞具有显著的治疗效果,能疏通闭塞血管,有效改善患者的神经功能缺损,具有可靠的可行性。