Fang Cuiyun, Fan Wei, Zhang Chunsheng, Yang Yi
Department of Nursing, Liyang People's Hospital, Liyang, China.
Department of Pediatrics, Liyang People's Hospital, Liyang, China.
Front Pediatr. 2022 Jun 29;10:925896. doi: 10.3389/fped.2022.925896. eCollection 2022.
To investigate the risk factors for benign convulsions with mild gastroenteritis (CwG) and provide a basis for the early identification and diagnosis.
We selected children with CwG and acute gastroenteritis in the same period who attended the pediatric department of the Liyang People's Hospital from June 2018 to June 2021. A retrospective analysis of the general data, clinical characteristics, and laboratory test results of the two groups was performed. Finally, we conducted a multifactorial logistic regression analysis to derive the risk factors for CwG.
A total of 82 children were included in the CwG and 93 children were included in the acute gastroenteritis group. Univariate analysis showed no significant differences in gender, age, vomiting, diarrhea, neutrophil, lymphocyte, hemoglobin, platelets, and serum calcium. Statistically significant differences were found in onset season, rotavirus, white blood cells, aspartate aminotransferase, alanine transaminase, serum sodium, and uric acid. Finally, multifactorial logistic regression analysis showed rotavirus (OR, 3.042, 95% CI, 1.116-8.289, = 0.030), serum sodium (OR, 0.811, 95% CI, 0.684-0.962, = 0.016) and uric acid (OR, 1.018, 95% CI, 1.012-1.024, = 0.000) to be independent risk factors.
Characteristics of gastroenteritis symptoms such as vomiting and diarrhea cannot be used to predict the onset of CwG. Rotavirus is an independent risk factor for CwG, and decreased serum sodium and increased uric acid can be used as early warning indicators for CwG.
探讨轻度胃肠炎伴良性惊厥(CwG)的危险因素,为早期识别与诊断提供依据。
选取2018年6月至2021年6月在溧阳市人民医院儿科就诊的同期CwG患儿及急性胃肠炎患儿。对两组患儿的一般资料、临床特征及实验室检查结果进行回顾性分析。最后进行多因素logistic回归分析得出CwG的危险因素。
CwG组共纳入82例患儿,急性胃肠炎组纳入93例患儿。单因素分析显示,两组在性别、年龄、呕吐、腹泻、中性粒细胞、淋巴细胞、血红蛋白、血小板及血清钙方面无显著差异。在发病季节、轮状病毒、白细胞、天冬氨酸转氨酶、丙氨酸转氨酶、血清钠及尿酸方面存在统计学显著差异。最后,多因素logistic回归分析显示轮状病毒(OR,3.042,95%CI,1.116 - 8.289,P = 0.030)、血清钠(OR,0.811,95%CI,0.684 - 0.962,P = 0.016)及尿酸(OR,1.018,95%CI,1.012 - 1.024,P = 0.000)为独立危险因素。
呕吐、腹泻等胃肠炎症状特点不能用于预测CwG的发病。轮状病毒是CwG的独立危险因素,血清钠降低及尿酸升高可作为CwG的预警指标。