Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Zhejiang, China.
Front Cell Infect Microbiol. 2022 Jul 1;12:892610. doi: 10.3389/fcimb.2022.892610. eCollection 2022.
Autophagy is an immune homeostasis process induced by multiple intracellular and extracellular signals. Inflammation is a protective response to harmful stimuli such as pathogen microbial infection and body tissue damage. infection elicits both autophagy and inflammation, and dysregulation of autophagy and inflammation promotes pathology. This review focuses on the interaction between autophagy and inflammation caused by infection, aiming to elaborate on the possible mechanism involved in the interaction.
自噬是一种由多种细胞内和细胞外信号诱导的免疫稳态过程。炎症是对病原体微生物感染和身体组织损伤等有害刺激的一种保护反应。感染会引发自噬和炎症，而自噬和炎症的失调会促进病理学的发生。本综述重点关注 感染引起的自噬和炎症之间的相互作用，旨在阐述相互作用中涉及的可能机制。
