R R Pravin, Chandran Suresh, Tan Yi Hua, Thomas Biju, Lee Jan Hau, Menon Anuradha P, Ong Kim Kiat, Kumar Pugalenthi Arun
General Pediatrics KK Women's & Children's Hospital Singapore.
Yong Loo Lin School of Medicine National University of Singapore Singapore.
Clin Case Rep. 2022 Jul 11;10(7):e5973. doi: 10.1002/ccr3.5973. eCollection 2022 Jul.
Extracorporeal membrane oxygenation (ECMO) is a life-saving rescue therapy used in acute respiratory failure refractory to invasive mechanical ventilation. Recent studies on positive outcomes of extended ECMO therapy are promising. We describe a case of a 2-year 8-month-old female child with necrotizing pneumonia secondary to , , and , who survived with intact neurological function and no long-term adverse outcomes after a prolonged ECMO run of 86 days. To the best of our knowledge, this is one of the longer durations of ECMO with transplant-free survival in a pediatric patient requiring respiratory support with good recovery and a good functional outcome. Allowing time for native lung recovery is pivotal for optimal recovery, despite significant lung injury due to the underlying disease process. With evolving ECMO experience, clinicians may need to re-consider the conventional maximum duration of ECMO in children with severe respiratory failure on a case-by-case basis.
体外膜肺氧合（ECMO）是一种用于治疗对有创机械通气难治的急性呼吸衰竭的挽救生命的治疗方法。近期关于延长ECMO治疗取得积极结果的研究很有前景。我们描述了一例2岁8个月大的女童，她因[此处原文缺失具体病因信息]继发坏死性肺炎，在接受了长达86天的ECMO治疗后存活，神经功能完好且无长期不良后果。据我们所知，这是儿科患者中ECMO持续时间较长且无需移植而存活的案例之一，该患者需要呼吸支持，恢复良好且功能预后良好。尽管潜在疾病过程导致严重肺损伤，但留出时间让肺自然恢复对于最佳恢复至关重要。随着ECMO经验的不断积累，临床医生可能需要根据具体情况重新考虑重症呼吸衰竭儿童ECMO的传统最长持续时间。
