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抗击新冠疫情及传染病的最优控制策略。

An optimal control policy in fighting COVID-19 and infectious diseases.

作者信息

Sayarshad Hamid R

机构信息

School of Civil Engineering, Cornell University, Ithaca, NY 14853, USA.

出版信息

Appl Soft Comput. 2022 Sep;126:109289. doi: 10.1016/j.asoc.2022.109289. Epub 2022 Jul 9.

Abstract

When an outbreak starts spreading, policymakers have to make decisions that affect the health of their citizens and the economy. Some might induce harsh measures, such as a lockdown. Following a long, harsh lockdown, the recession forces policymakers to rethink reopening. To provide an effective strategy, here we propose a control strategy model. Our model assesses the trade-off between social performance and limited medical resources by determining individuals' propensities. The proposed strategy also helps decision-makers to find optimal lockdown and exit strategies for each region. Moreover, the financial loss is minimized. We use the public sentiment information during the pandemic to determine the percentage of individuals with high-risk behavior and the percentage of individuals with low-risk behavior. Hence, we propose an online platform using fear-sentiment information to estimate the personal protective equipment (PPE) burn rate overtime for the entire population. In addition, a study of a COVID-19 dataset for Los Angeles County is performed to validate our model and its results. The total social cost reduces by 18% compared with a control strategy where susceptible individuals are assumed to be homogeneous. We also reduce the total social costs by 26% and 22% compared to other strategies that consider the health-care cost or the social performance cost, respectively.

摘要

当疫情开始蔓延时,政策制定者必须做出影响公民健康和经济的决策。一些人可能会采取严厉措施,比如封锁。经过漫长而严厉的封锁后,经济衰退迫使政策制定者重新思考解封问题。为了提供一种有效的策略,我们在此提出一种控制策略模型。我们的模型通过确定个体的倾向来评估社会绩效与有限医疗资源之间的权衡。所提出的策略还能帮助决策者为每个地区找到最佳的封锁和解封策略。此外,能将经济损失降至最低。我们利用疫情期间的公众情绪信息来确定高风险行为个体的比例和低风险行为个体的比例。因此,我们提出一个利用恐惧情绪信息的在线平台,以估计整个人口随时间推移的个人防护装备(PPE)消耗率。此外,对洛杉矶县的新冠疫情数据集进行了研究,以验证我们的模型及其结果。与假设易感个体同质化的控制策略相比,社会总成本降低了18%。与分别考虑医疗成本或社会绩效成本的其他策略相比,我们还将社会总成本分别降低了26%和22%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8c9/9270838/47e666feae22/gr1_lrg.jpg

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