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95例患者扁平足严重程度与膝关节骨关节炎症状之间存在强相关性。

A Strong Correlation Between the Severity of Flatfoot and Symptoms of Knee Osteoarthritis in 95 Patients.

作者信息

Zhang Min, Nie Mao-Dan, Qi Xin-Zheng, Ke Song, Li Jun-Wei, Shui Yang-Yang, Zhang Zhuo-Yue, Wang Min, Cheng Cheng-Kung

机构信息

Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.

School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.

出版信息

Front Surg. 2022 Jun 30;9:936720. doi: 10.3389/fsurg.2022.936720. eCollection 2022.

Abstract

OBJECTIVE

The purpose of this study is to assess the association between the presence and severity of flatfoot and symptoms of knee OA.

METHODS

95 participants with knee OA were recruited from a patient cohort at a regional hospital. Symptoms of knee OA, including knee degeneration, femorotibial alignment, pain, stiffness and dysfunction were assessed using the Kellgren-Lawrence (K-L) grading system, femoral-tibial angle (FTA), and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Participants were divided into groups with flatfoot (mild, moderate and severe) and without flatfoot based on the Clarke's angle. Linear regression and ordinal logistic regression were used for statistical analysis, as appropriate.

RESULTS

Having flatfoot was associated with a significantly increased risk of having a higher K-L grade (OR: 20.03; 95% CI, 5.88, 68.27;  < 0.001), smaller FTA (Beta: -2.96; 95% CI, -4.41, -1.50;  < 0.001), higher pain score (Beta: 0.47; 95% CI, 0.24, 0.69;  < 0.001) and greater loss of function (Beta: 0.25; 95% CI, 0.02, 0.48;  = 0.03). Severe grades of flat feet were associated with a higher K-L grade (OR: 0.19; 95% CI, 0.08, 0.44;  < 0.001), smaller FTA (Beta: 1.51; 95% CI, 0.66, 2.35;  = 0.001), higher pain score (Beta: -0.25; 95% CI, -0.39, -0.11;  = 0.001), greater stiffness (Beta: -0.24; 95% CI, -0.38, -0.09;  = 0.002) and greater loss of function (Beta: -0.27; 95% CI, -0.41, -0.14;  < 0.001).

CONCLUSION

The results indicated that the severity of flattening is significantly associated with symptoms of knee OA. For the conservative management of knee OA, both flatfoot and its severity should be carefully considered.

摘要

目的

本研究旨在评估扁平足的存在及严重程度与膝骨关节炎症状之间的关联。

方法

从一家地区医院的患者队列中招募了95名膝骨关节炎患者。使用凯尔格伦-劳伦斯(K-L)分级系统、股胫角(FTA)以及西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评估膝骨关节炎的症状,包括膝关节退变、股胫对线、疼痛、僵硬和功能障碍。根据克拉克角将参与者分为有扁平足(轻度、中度和重度)和无扁平足两组。酌情使用线性回归和有序逻辑回归进行统计分析。

结果

患有扁平足与K-L分级较高(比值比:20.03;95%置信区间,5.88,68.27;P<0.001)、FTA较小(β:-2.96;95%置信区间,-4.41,-1.50;P<0.001)、疼痛评分较高(β:0.47;95%置信区间,0.24,0.69;P<0.001)以及功能丧失更严重(β:0.25;95%置信区间,0.02,0.48;P = 0.03)的风险显著增加相关。重度扁平足与较高的K-L分级(比值比:0.19;95%置信区间,0.08,0.44;P<0.001)、较小的FTA(β:1.51;95%置信区间,0.66,2.35;P = 0.001)、较高的疼痛评分(β:-0.25;95%置信区间,-0.39,-0.11;P = 0.001)、更严重的僵硬(β:-0.24;95%置信区间,-0.38,-0.09;P = 0.002)以及功能丧失更严重(β:-0.27;95%置信区间,-0.41,-0.14;P<0.001)相关。

结论

结果表明扁平足的严重程度与膝骨关节炎症状显著相关。对于膝骨关节炎的保守治疗,应仔细考虑扁平足及其严重程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e710/9280043/85db9efda09c/fsurg-09-936720-g001.jpg

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