Aldridge Chad M, McDonald Mark M, Wruble Mattia, Zhuang Yan, Uribe Omar, McMurry Timothy L, Lin Iris, Pitchford Haydon, Schneider Brett J, Dalrymple William A, Carrera Joseph F, Chapman Sherita, Worrall Bradford B, Rohde Gustavo K, Southerland Andrew M
Department of Neurology, University of Virginia, Charlottesville, VA, United States.
Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, VA, United States.
Front Neurol. 2022 Jul 1;13:878282. doi: 10.3389/fneur.2022.878282. eCollection 2022.
Current EMS stroke screening tools facilitate early detection and triage, but the tools' accuracy and reliability are limited and highly variable. An automated stroke screening tool could improve stroke outcomes by facilitating more accurate prehospital diagnosis and delivery. We hypothesize that a machine learning algorithm using video analysis can detect common signs of stroke. As a proof-of-concept study, we trained a computer algorithm to detect presence and laterality of facial weakness in publically available videos with comparable accuracy, sensitivity, and specificity to paramedics.
We curated videos of people with unilateral facial weakness ( = 93) and with a normal smile ( = 96) from publicly available web-based sources. Three board certified vascular neurologists categorized the videos according to the presence or absence of weakness and laterality. Three paramedics independently analyzed each video with a mean accuracy, sensitivity and specificity of 92.6% [95% CI 90.1-94.7%], 87.8% [95% CI 83.9-91.7%] and 99.3% [95% CI 98.2-100%]. Using a 5-fold cross validation scheme, we trained a computer vision algorithm to analyze the same videos producing an accuracy, sensitivity and specificity of 88.9% [95% CI 83.5-93%], 90.3% [95% CI 82.4-95.5%] and 87.5 [95% CI 79.2-93.4%].
These preliminary results suggest that a machine learning algorithm using computer vision analysis can detect unilateral facial weakness in pre-recorded videos with an accuracy and sensitivity comparable to trained paramedics. Further research is warranted to pursue the concept of augmented facial weakness detection and external validation of this algorithm in independent data sets and prospective patient encounters.
当前的急诊医疗服务(EMS)中风筛查工具有助于早期发现和分诊,但这些工具的准确性和可靠性有限且差异很大。一种自动化中风筛查工具可以通过促进更准确的院前诊断和转运来改善中风治疗效果。我们假设使用视频分析的机器学习算法可以检测中风的常见体征。作为一项概念验证研究,我们训练了一种计算机算法,以在公开可用的视频中检测面部无力的存在和偏向性,其准确性、敏感性和特异性与护理人员相当。
我们从公开的基于网络的来源中挑选了单侧面部无力患者的视频(n = 93)和微笑正常的视频(n = 96)。三位获得董事会认证的血管神经科医生根据是否存在无力和偏向性对视频进行分类。三名护理人员独立分析每个视频,平均准确率、敏感性和特异性分别为92.6% [95%置信区间90.1 - 94.7%]、87.8% [95%置信区间83.9 - 91.7%]和99.3% [95%置信区间98.2 - 100%]。使用5折交叉验证方案,我们训练了一种计算机视觉算法来分析相同的视频,其准确率、敏感性和特异性分别为88.9% [95%置信区间83.5 - 93%]、90.3% [95%置信区间82.4 - 95.5%]和87.5 [95%置信区间79.2 - 93.4%]。
这些初步结果表明,使用计算机视觉分析的机器学习算法可以在预先录制的视频中检测单侧面部无力,其准确性和敏感性与训练有素的护理人员相当。有必要进行进一步研究,以推进增强面部无力检测的概念,并在独立数据集和前瞻性患者病例中对该算法进行外部验证。