The health risk assessment of heavy metals to human health through the consumption of spp and catfish caught from Lake Mariut, Egypt.

This work assesses the concentration of As, Cd, Pb, Hg, and Al in three of Tilapia species and catfish caught from Lake Mariut. As well as the human health risk and muscle biochemical composition. Besides, the antioxidant responses of different species. The average metal concentration order was Pb> As> Cd> Al> Hg. The Cd and Pb levels in all species; besides, the Hg levels in and exceeded the maximum limits set by FAO, European legislation, and FAO/WHO. The human health risk was assessed using estimated dietary intakes, the target hazard quotient (THQ), and the carcinogenic risk (CR). THQ was >1 in all examined fishes and closer to 1 in THQ. As well, CR level for As was higher than the permissible value. showed significant decreases in carbohydrates compared to ; also, ash content compared to and . Furthermore, water content compared to . In contrast, significant increases of SOD in compared to . In addition, CAT and GPx in compared to . Also, GR in both and compared to and GSH in all of spp. compared to . Data obtained provide evidence of health risks to the consumers. Therefore, more caution is required.