He Tao, Zong Lei, Pan Peng, Sun Shanming, Qu Hongmei
Department of Clinical Medical College, Weifang Medical University, Weifang, China.
Department of Gastroenterology, The First Affiliated Hospital of Weifang Medical College, Weifang People's Hospital, Weifang, China.
Front Med (Lausanne). 2022 Jun 30;9:869981. doi: 10.3389/fmed.2022.869981. eCollection 2022.
This study investigated the predictive value of narrow-band imaging (NBI) endoscopic staging of different mucosal vascular patterns (MVPs) in patients with ulcerative colitis (UC) for histological healing or clinical recurrence of patients with UC. A total of 124 patients with UC in clinical remission attending the First Affiliated Hospital of Weifang Medical College were included in the study and underwent NBI colonoscopy. Inflammatory activity was assessed in the intestine using the Mayo endoscopic score (MES) and the MVP. Mucosal inflammation was histologically graded using the Nancy index (NI). The colons of 124 patients with UC were staged according to NBI endoscopic MVP staging criteria. The differences between NBI colonoscopy MVP typing and white light endoscopic MES in assessing histological healing (HH) were statistically significant ( < 0.001), and there was a moderate correlation between MES and the degree of HH ( = 0.471, < 0.001). In addition, there was a significant correlation between the severity of mucosal activity determined by white light endoscopy (WLE) and MVP staging ( = 0.811, < 0.001). The differences between NBI endoscopic MVP staging and white light endoscopic MES in assessing UC recurrence were statistically significant ( < 0.001). Spearman's correlation analysis showed a moderate correlation between NBI endoscopic MVP staging and clinical recurrence. NBI endoscopic MVP staging can predict HH and clinical recurrence status better than WLE.
本研究探讨窄带成像（NBI）内镜下不同黏膜血管形态（MVP）对溃疡性结肠炎（UC）患者组织学愈合或临床复发的预测价值。潍坊医学院附属医院共纳入124例临床缓解期的UC患者，对其进行NBI结肠镜检查。采用梅奥内镜评分（MES）和MVP评估肠道炎症活动度。采用南希指数（NI）对黏膜炎症进行组织学分级。根据NBI内镜MVP分期标准对124例UC患者的结肠进行分期。NBI结肠镜检查MVP分型与白光内镜MES在评估组织学愈合（HH）方面的差异具有统计学意义（<0.001），MES与HH程度之间存在中度相关性（=0.471，<0.001）。此外，白光内镜（WLE）确定的黏膜活动度严重程度与MVP分期之间存在显著相关性（=0.811，<0.001）。NBI内镜MVP分期与白光内镜MES在评估UC复发方面的差异具有统计学意义（<0.001）。Spearman相关性分析显示NBI内镜MVP分期与临床复发之间存在中度相关性。NBI内镜MVP分期在预测HH和临床复发状态方面比WLE表现更好。
