Department of Interdisciplinary Endoscopy, I. Medizinische Klinik und Poliklinik, University Hospital, Mainz, Germany.
Gastroenterology and Digestive Endoscopy Unit, IRCCS Policlinico San Donato, Milan, Italy.
Dig Endosc. 2018 Jul;30(4):441-448. doi: 10.1111/den.13023. Epub 2018 Feb 19.
Crohn's disease and ulcerative colitis are chronic inflammatory bowel diseases (IBD) causing severe damage of the luminal gastrointestinal tract. Differential diagnosis between both disease entities is sometimes awkward requiring a multifactorial pathway, including clinical and laboratory data, radiological findings, histopathology and endoscopy. Apart from disease diagnosis, endoscopy in IBD plays a major role in prediction of disease severity and extent (i.e. mucosal healing) for tailored patient management and for screening of colitis-associated cancer and its precursor lesions. In this state-of-the-art review, we focus on current applications of endoscopy for diagnosis and surveillance of IBD. Moreover, we will discuss the latest guidelines on surveillance and provide an overview of the most recent developments in the field of endoscopic imaging and IBD.
克罗恩病和溃疡性结肠炎是慢性炎症性肠病（IBD），可导致胃肠道内腔严重损伤。这两种疾病实体之间的鉴别诊断有时比较棘手，需要采用多因素途径，包括临床和实验室数据、影像学发现、组织病理学和内镜检查。除了疾病诊断，IBD 内镜在预测疾病严重程度和范围（即黏膜愈合）方面也起着重要作用，以实现个体化患者管理，并筛查结肠炎相关癌症及其前病变。在这篇最新综述中，我们重点介绍内镜在 IBD 的诊断和监测中的应用。此外，我们还将讨论最新的监测指南，并概述内镜成像和 IBD 领域的最新进展。
