Institute of Environmental Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan.
Department of Life Sciences, National Central University, Jhongli City, Taoyuan, Taiwan.
J Basic Microbiol. 2022 Oct;62(10):1193-1201. doi: 10.1002/jobm.202200106. Epub 2022 Jul 18.
Pseudomonas sp. A46 was first isolated from mercury-contaminated groundwater in Taiwan. This study is the first to report the draft whole-genome sequence of Pseudomonas sp. A46. Its genome consists of 126 contigs, with a total length of 6,782,516 bp and a GC content of 64.7%. Phylogenetic analysis based on 16 S rRNA gene sequences revealed that Pseudomonas sp. A46 is closely related to Pseudomonas citronellolis. Assessment of the draft genome sequence revealed that Pseudomonas sp. A46 harbors sets of genes conferring resistance to heavy metals, such as mercury, zinc, lead, copper, cadmium, chromate, and arsenate. These identified genes enable this bacterium to tolerate heavy metal stress.
铜绿假单胞菌 A46 最初从台湾受汞污染的地下水分离得到。本研究首次报道了铜绿假单胞菌 A46 的全基因组序列草案。其基因组由 126 个连续片段组成,全长 6782516bp,GC 含量为 64.7%。基于 16S rRNA 基因序列的系统发育分析表明,铜绿假单胞菌 A46 与柠檬假单胞菌密切相关。对基因组序列草案的评估表明,铜绿假单胞菌 A46 含有多组赋予其重金属抗性的基因,如汞、锌、铅、铜、镉、铬酸盐和砷酸盐。这些鉴定出的基因使该细菌能够耐受重金属胁迫。