Department of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Department of Orthopaedics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Fam Pract. 2023 Feb 9;40(1):75-82. doi: 10.1093/fampra/cmac074.
To explore characteristics of nocturnal pain and to identify differences in participants' characteristics and osteoarthritis (OA) symptoms between hip and knee OA participants with and without nocturnal pain.
Data for this exploratory cross-sectional study were obtained from an online survey, distributed through social media and patient associations in the period from April 2020 until May 2020, which was conducted in 101 participants with (self-reported) hip or knee OA. Descriptive statistics were used to provide insight into the characteristics of the study population. Pain intensity, localization, dimension, and impact of (nocturnal) pain on sleep were described and compared with daytime pain.
Nocturnal pain was reported by 76/101 (75%) participants. Participants with nocturnal pain scored higher visual analogue scale (VAS) scores for their nocturnal pain compared with their pain at the moment (respectively: median VAS score 49.5 vs. 40.0). Their day pain rating indexes of sensory-discriminative dimension were higher compared with their nocturnal pain. Comparison between participants with and without nocturnal pain showed that participants with nocturnal pain were affected by intermittent, constant, and radiating pain. Pain had more impact on their sleep and they scored their pain at its worst higher compared with participants without nocturnal pain.
In participants with nocturnal pain (75%), we found that their VAS pain scores were not in harmony with their pain expressed in words. This study increases awareness of nocturnal pain in OA patients in general practice. More research is needed to provide general practitioners possible interventions for patients with OA and nocturnal pain.
探索夜间疼痛的特征，并确定有和无夜间疼痛的髋部和膝部骨关节炎（OA）患者在患者特征和 OA 症状方面的差异。
本探索性横断面研究的数据来自于 2020 年 4 月至 2020 年 5 月期间通过社交媒体和患者协会在线调查收集的 101 名（自我报告）髋部或膝部 OA 患者的数据。使用描述性统计数据深入了解研究人群的特征。描述了疼痛强度、定位、维度以及（夜间）疼痛对睡眠的影响，并与日间疼痛进行了比较。
76/101（75%）名参与者报告有夜间疼痛。与当时的疼痛相比，有夜间疼痛的参与者夜间疼痛的视觉模拟量表（VAS）评分更高（分别为：中值 VAS 评分 49.5 vs. 40.0）。他们的日间疼痛感觉区分维度的疼痛评分指数高于夜间疼痛。有和无夜间疼痛的参与者之间的比较表明，有夜间疼痛的参与者受到间歇性、持续性和放射性疼痛的影响。疼痛对他们的睡眠影响更大，与无夜间疼痛的参与者相比，他们对疼痛的评分更高。
在有夜间疼痛（75%）的参与者中，我们发现他们的 VAS 疼痛评分与他们用言语表达的疼痛不一致。本研究提高了初级保健医生对 OA 患者夜间疼痛的认识。需要进一步研究为 OA 和夜间疼痛患者的初级保健医生提供可能的干预措施。
