Jaseng Hospital of Korean Medicine, Seoul, Republic of Korea.
Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul, Republic of Korea.
PLoS One. 2020 Nov 12;15(11):e0242077. doi: 10.1371/journal.pone.0242077. eCollection 2020.
This study aims to investigate the association between mental health and quality of life of osteoarthritis (OA) patients according to the site of pain.
Retrospective cross-sectional study.
Data of 22,948 participants of the sixth Korea National Health and Nutrition Examination Survey conducted from 2013-2015 were used.
Participants were asked if they had OA pain in the hip joint, knee joint, and lower back (yes/no) and whether they experienced anxiety or depression. The EQ-5D questionnaire was used to determine the quality of life of patients with hip, knee, and lower back OA. Multiple logistic regression analysis was performed after adjusting.
A total of 5,401 patients reported pain in the hip joint, knee joint, or lower back. The analysis showed significant relations between pain sites, mental health, and quality of life. First, more female patients with OA experienced stress and depression than males. Second, for males with OA, stress was reported in the order of: lower back > hip > knee, while pain and depression was reported in the order of: lower back > knee > hip (p < 0.05). For females with OA, stress was reported in the order of: knee > lower back > hip, while depression was reported in the order of: knee > lower back > hip. Third, considering quality of life, for males, hip joint pain had the greatest impact on quality of life and for females, knee joint pain had the largest impact (p < 0.001).
For patients with OA, the effect on the mental health and quality of life differed according to sex and sites of pain. Therefore, this study confirms that pain sites, sex, mental health, and quality of life are independent risk factors when determining OA pain.
本研究旨在根据疼痛部位探讨关节炎（OA）患者的心理健康与生活质量之间的关系。
回顾性横断面研究。
使用了 2013-2015 年进行的第六届韩国国家健康与营养检查调查的 22948 名参与者的数据。
询问参与者髋关节、膝关节和下背部是否有 OA 疼痛（是/否），以及他们是否经历过焦虑或抑郁。使用 EQ-5D 问卷确定髋关节、膝关节和下背部 OA 患者的生活质量。在调整后进行多变量逻辑回归分析。
共有 5401 名患者报告髋关节、膝关节或下背部疼痛。分析显示疼痛部位、心理健康和生活质量之间存在显著关系。首先，患有 OA 的女性患者比男性患者更易出现压力和抑郁。其次，对于患有 OA 的男性，压力的报告顺序为：下背部>髋关节>膝关节，而疼痛和抑郁的报告顺序为：下背部>膝关节>髋关节（p<0.05）。对于患有 OA 的女性，压力的报告顺序为：膝关节>下背部>髋关节，而抑郁的报告顺序为：膝关节>下背部>髋关节。第三，考虑生活质量，对于男性，髋关节疼痛对生活质量的影响最大，对于女性，膝关节疼痛的影响最大（p<0.001）。
对于 OA 患者，心理健康和生活质量的影响因性别和疼痛部位而异。因此，本研究证实疼痛部位、性别、心理健康和生活质量是确定 OA 疼痛的独立危险因素。
