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普氏野马血液标志物的遗传学研究。

Genetic studies of blood markers in Przewalski's horses.

作者信息

Bowling A T, Ryder O A

出版信息

J Hered. 1987 Mar-Apr;78(2):75-80. doi: 10.1093/oxfordjournals.jhered.a110340.

DOI:10.1093/oxfordjournals.jhered.a110340
PMID:3584938
Abstract

Ninety-six Przewalski's horses (Equus przewalskii) were blood typed using systems of inherited blood variants known to be highly effective for parentage testing of domestic horses (E. caballus). Sixteen red cell antigenic factors detected using sera prepared by alloimmunization of domestic horses were shown to be inherited in six systems (A, C, D, P, Q, and U) and in the same patterns as domestic horses. Family data confirmed autosomal, codominant inheritance at five loci of serum protein variants (Al, Tf, Xk, Pi, and Es) and three loci of red cell proteins (PGM, PHI, and Hb). One serum protein locus (Gc) and two red cell protein loci (PGD and CA) appeared to be monomorphic. Despite the narrow genetic base and high inbreeding coefficients of captive Przewalski's horses, average heterozygosity calculated over 18 loci was estimated to be 0.320 +/- 0.05, which was similar to that found in five breeds of domestic horses.

摘要

利用已知对家马(马属马种)亲子鉴定非常有效的遗传血液变异系统,对96匹普氏野马(普氏野马种)进行了血型鉴定。通过家马同种免疫制备的血清检测到的16种红细胞抗原因子,被证明在六个系统(A、C、D、P、Q和U)中遗传,且遗传模式与家马相同。家系数据证实了血清蛋白变异体的五个位点(Al、Tf、Xk、Pi和Es)以及红细胞蛋白的三个位点(PGM、PHI和Hb)存在常染色体共显性遗传。一个血清蛋白位点(Gc)和两个红细胞蛋白位点(PGD和CA)似乎是单态的。尽管圈养普氏野马的遗传基础狭窄且近亲繁殖系数高,但在18个位点上计算出的平均杂合度估计为0.320±0.05,这与在五个家马品种中发现的杂合度相似。

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