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印度艾滋病毒流行转变中的多样性:艾滋病毒流行病学指标和基准的应用。

Diversity in HIV epidemic transitions in India: An application of HIV epidemiological metrices and benchmarks.

机构信息

National AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India.

Indian Council of Medical Research-National Institute of Medical Statistics, New Delhi, India.

出版信息

PLoS One. 2022 Jul 18;17(7):e0270886. doi: 10.1371/journal.pone.0270886. eCollection 2022.

Abstract

BACKGROUND

The Joint United Nations Programme on AIDS (UNAIDS) has emphasized on the incidence-prevalence ratio (IPR) and incidence-mortality ratio (IMR) to measure the progress in HIV epidemic control. In this paper, we describe the status of epidemic control in India and in various states in terms of UNAIDS's recommended metrices.

METHOD

The National AIDS Control Programme (NACP) of India spearheads work on mathematical modelling to estimate HIV burden based on periodically conducted sentinel surveillance for providing guidance to program implementation and policymaking. Using the results of the latest round of HIV Estimations in 2019, IPR and IMR were calculated.

RESULTS

National level IPR was 0.029 [0.022-0.037] in 2019 and ranged from 0.01 to 0.15 in various States and Union Territories (UTs). Corresponding Incidence-Mortality Ratio was at 0.881 [0.754-1.014] nationally and ranged between 0.20 and 12.90 across the States/UTs.

CONCLUSIONS

Based on UNAIDS recommended indicators for HIV epidemic control, namely IPR and IMR; national AIDS response in India appears on track. However, the program success is not uniform and significant heterogeneity as well as expanding epidemic was observed at the level of States or UTs. Reinforcing States/UTs specific and focused HIV prevention, testing and treatment initiatives may help in the attainment of 2030 Sustainable Development Goals of ending AIDS as a public health threat by 2030.

摘要

背景

联合国艾滋病规划署(UNAIDS)强调发病率-流行率比(IPR)和发病率-死亡率比(IMR),以衡量艾滋病毒流行控制的进展。本文根据 UNAIDS 推荐的指标,描述了印度及各邦在艾滋病毒流行控制方面的现状。

方法

印度国家艾滋病控制计划(NACP)带头进行数学建模工作,根据定期进行的哨点监测来估计艾滋病毒负担,为方案实施和决策提供指导。利用 2019 年最新一轮艾滋病毒估计结果,计算了 IPR 和 IMR。

结果

2019 年全国 IPR 为 0.029[0.022-0.037],各邦和联邦属地(UTs)的范围为 0.01-0.15。相应的发病率-死亡率比为 0.881[0.754-1.014],全国范围内的范围为 0.20-12.90。

结论

根据 UNAIDS 推荐的艾滋病毒流行控制指标,即 IPR 和 IMR,印度的国家艾滋病应对措施似乎正在取得进展。然而,方案的成功并非一致,在邦或联邦属地一级观察到显著的异质性和不断扩大的疫情。加强邦/联邦属地特定和有针对性的艾滋病毒预防、检测和治疗举措,可能有助于实现 2030 年可持续发展目标,即在 2030 年之前消除艾滋病这一公共卫生威胁。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb49/9292090/88f7d28a5024/pone.0270886.g001.jpg

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