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Polygenic Risk Scores for Follow Up After Colonoscopy and Polypectomy: Another Tool for Risk Stratification and Planning Surveillance?

作者信息

Gupta Samir, Thrift Aaron P

机构信息

Jennifer Moreno Veterans Affairs Medical Center, San Diego, California; Division of Gastroenterology and the Moores Cancer Center, University of California San Diego, La Jolla, California.

Section of Epidemiology and Population Sciences, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.

出版信息

Clin Gastroenterol Hepatol. 2023 Jan;21(1):29-32. doi: 10.1016/j.cgh.2022.06.025. Epub 2022 Jul 15.

DOI:10.1016/j.cgh.2022.06.025
PMID:35850412
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9789161/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2643/9789161/96a0a0a064a3/nihms-1825333-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2643/9789161/96a0a0a064a3/nihms-1825333-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2643/9789161/96a0a0a064a3/nihms-1825333-f0001.jpg

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2
Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study.采用遗传和环境风险评分组合对早发性结直肠癌进行风险分层:一项国际多中心研究。
J Natl Cancer Inst. 2022 Apr 11;114(4):528-539. doi: 10.1093/jnci/djac003.
3
Aberrant DNA methylation patterns in microsatellite stable human colorectal cancers define a new marker panel for the CpG island methylator phenotype.
微卫星稳定的人类结直肠癌中异常的 DNA 甲基化模式定义了 CpG 岛甲基化表型的新标志物面板。
Int J Cancer. 2022 Feb 15;150(4):617-625. doi: 10.1002/ijc.33831. Epub 2021 Oct 13.
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Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement.结直肠癌筛查:美国预防服务工作组推荐声明。
JAMA. 2021 May 18;325(19):1965-1977. doi: 10.1001/jama.2021.6238.
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Methylated circulating tumor DNA as a biomarker for colorectal cancer diagnosis, prognosis, and prediction.甲基化循环肿瘤 DNA 作为结直肠癌诊断、预后和预测的生物标志物。
Clin Epigenetics. 2021 May 17;13(1):111. doi: 10.1186/s13148-021-01095-5.
6
Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk.全基因组建模分析多基因风险评分在结直肠癌风险中的作用。
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