Oncology Data Analytics Programme, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain; Gastroenterology Department, Bellvitge University Hospital, L'Hospitalet de Llobregat, Spain; Colorectal Cancer Research Group, ONCOBELL Programme, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) , L'Hospitalet de Llobregat, Spain; CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Oncology Data Analytics Programme, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain; Colorectal Cancer Research Group, ONCOBELL Programme, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) , L'Hospitalet de Llobregat, Spain; CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Gastroenterol Hepatol. 2022 Jun-Jul;45(6):474-487. doi: 10.1016/j.gastrohep.2021.11.005. Epub 2021 Nov 27.
Although adenomas and serrated polyps are the preneoplastic lesions of colorectal cancer, only few of them will eventually progress to cancer. This review provides a comprehensive overview of the present and future of post-polypectomy colonoscopy surveillance. Post-polypectomy surveillance guidelines have recently been updated and all share the aim towards more selective and less frequent surveillance. We have examined these current guidelines and compared the recommendations of each of them. To improve the diagnostic yield of post-polypectomy surveillance it is important to find predictors of metachronous polyps that better identify high-risk individuals of developing advanced neoplasia. For this reason, we have also conducted a literature review of the molecular biomarkers of metachronous advanced colorectal polyps. Finally, we have discussed future directions of post-polypectomy surveillance and identified possible strategies to improve the use of endoscopic resources with the COVID-19 pandemic.
虽然腺瘤和锯齿状息肉是结直肠癌的癌前病变，但其中只有少数最终会发展为癌症。本综述全面概述了结直肠息肉切除术后结肠镜检查监测的现状和未来。结直肠息肉切除术后监测指南最近已经更新，所有指南都旨在进行更具选择性和更少频率的监测。我们检查了这些现行指南，并比较了它们各自的建议。为了提高结直肠息肉切除术后监测的诊断效果，找到预测腺瘤性息肉的指标以更好地识别发生高级别肿瘤的高危个体非常重要。为此，我们还对结直肠息肉切除术后发生的进展期腺瘤的分子生物标志物进行了文献回顾。最后，我们讨论了结直肠息肉切除术后监测的未来方向，并确定了在 COVID-19 大流行期间可能的策略来改进内镜资源的使用。
