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急性冠脉综合征后新发心房颤动:患病率及预测因素。

New-onset atrial fibrillation after acute coronary syndrome: prevalence and predictive factors.

出版信息

Tunis Med. 2022;100(2):114-121.

PMID:35852244
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9272446/
Abstract

INTRODUCTION

New-onset AF atrial fibrillation (NOAF) frequently complicates acute coronary syndromes (ACS) leading to adverse outcomes in the short and long term. The prevalence of NOAF in patients hospitalized for ACS is variably reported and ranges between 2 and 37%. Several predictor factors have been implicated in the literature but remain a subject of controversy.

AIM

To determine the prevalence of NOAF in a population of patients admitted for ACS and to identify its predictive factors.

METHODS

We carried out a prospective, descriptive and comparative observational study in hospitalized patients with ACS who did not have a previous diagnosis of AF.

RESULTS

In our study, we included 404 patients hospitalized for ACS. The prevalence of NOAF was 10%. In the multivariate analytical study, we retained as independent predictors of NOAF: age greater than 62 years (p = 0.04; adjusted OR = 4.83; CI95%: 1.07-21.77), chronic renal failure (p = 0.043; adjusted OR = 6.61; CI95%: 1.06-35.80), history of stroke (p = 0.002; adjusted OR = 44.51; CI95%: 3.97- 498.10) and finally uricemia greater than or equal to 62 mg / l (p = 0.04; adjusted OR = 4.4; CI95%: 1.06-18.15).

CONCLUSIONS

The prevalence of NOAF in patients with ACS was 10%. Its systematic screening in these patients appears to be a relevant approach because of the strong association between these two pathologies.

摘要

引言

新发心房颤动(NOAF)常合并急性冠状动脉综合征(ACS),导致短期和长期不良结局。NOAF 在 ACS 住院患者中的发生率存在差异报道,范围为 2%至 37%。一些预测因素已在文献中提及,但仍存在争议。

目的

确定 ACS 住院患者中 NOAF 的发生率,并确定其预测因素。

方法

我们对未诊断为 AF 的 ACS 住院患者进行了前瞻性、描述性和比较观察性研究。

结果

在我们的研究中,我们纳入了 404 例 ACS 住院患者。NOAF 的发生率为 10%。在多变量分析研究中,我们保留了以下作为 NOAF 的独立预测因素:年龄大于 62 岁(p = 0.04;调整后的 OR = 4.83;95%CI:1.07-21.77)、慢性肾功能衰竭(p = 0.043;调整后的 OR = 6.61;95%CI:1.06-35.80)、中风史(p = 0.002;调整后的 OR = 44.51;95%CI:3.97-498.10)和最终尿酸水平大于或等于 62mg / l(p = 0.04;调整后的 OR = 4.4;95%CI:1.06-18.15)。

结论

ACS 患者中 NOAF 的发生率为 10%。在这些患者中对其进行系统筛查似乎是一种有效的方法,因为这两种疾病之间存在很强的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c5f/9272446/0c25ec5b84d9/image2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c5f/9272446/1114e0615a64/image1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c5f/9272446/0c25ec5b84d9/image2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c5f/9272446/1114e0615a64/image1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c5f/9272446/0c25ec5b84d9/image2.jpg

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