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弹性硅酮封闭性敷料与硅酮封闭性敷料治疗瘢痕的随机对照试验

Elastic Silicone Occlusive Sheeting Versus Silicone Occlusive Sheeting in the Treatment of Scars: A Randomized Controlled Trial.

作者信息

Jiang Min, Zhang Yi, Xiang Qiang, Luo Qilin, Wen Fengxia, Jiang Xupin, Liu Jie, Zhang Ze, Wu Chao, Zhang Jiaping

机构信息

Department of Plastic Surgery, State Key Laboratory of Trauma, Burns and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.

Department of Breast Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.

出版信息

Dermatol Ther (Heidelb). 2022 Aug;12(8):1809-1821. doi: 10.1007/s13555-022-00763-5. Epub 2022 Jul 19.

DOI:10.1007/s13555-022-00763-5
PMID:35852693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9357594/
Abstract

INTRODUCTION

Hypertrophic scarring caused by conventional open thyroidectomy is prevalent among Asians and published trials have proved that silicone occlusive sheeting is a useful treatment for hypertrophic scarring. However, silicone occlusive sheeting does not effectively prevent scar widening. Here, we report elastic silicone occlusive sheeting as a new type of silicone application. In this study, we compared the effects of elastic silicone occlusive sheeting on scar width and appearance after conventional open thyroidectomy with those of silicone occlusive sheeting.

METHODS

In this prospective, randomized, assessor-blinded study, a total of 74 patients who underwent conventional open thyroidectomy were recruited to undergo elastic silicone occlusive sheeting and silicone occlusive sheeting on the healed wound. Split scar study and scar quality were assessed on the basis of scar width, Vancouver scar scale, pain/itching visual analogue scale, and patients' subjective degree of satisfaction with the scar, during the patients' 6-month review.

RESULTS

A total of 61 patients completed the study. Scar width, Vancouver scar scale score, and patients' subjective degree of satisfaction indicated that elastic silicone occlusive sheeting was associated with narrower scars and significant improvement in scar appearance. The two methods did not differ significantly with regard to pain/itching visual analogue scale.

CONCLUSIONS

Our findings highlight elastic silicone occlusive sheeting as an effective treatment for scarring, resulting in narrower and better scars after conventional open thyroidectomy. The use of elastic silicone occlusive sheeting after conventional open thyroidectomy may minimize the formation of hypertrophic scars in the early postoperative period.

TRIAL REGISTRATION

ChiCTR2100049740.

摘要

引言

传统开放性甲状腺切除术导致的增生性瘢痕在亚洲人中很常见,已发表的试验证明硅胶封闭片是治疗增生性瘢痕的有效方法。然而,硅胶封闭片并不能有效防止瘢痕增宽。在此,我们报告一种新型硅胶应用——弹性硅胶封闭片。在本研究中,我们比较了弹性硅胶封闭片与硅胶封闭片对传统开放性甲状腺切除术后瘢痕宽度和外观的影响。

方法

在这项前瞻性、随机、评估者盲法研究中,共招募了74例行传统开放性甲状腺切除术的患者,在愈合的伤口上使用弹性硅胶封闭片和硅胶封闭片。在患者6个月复查时,根据瘢痕宽度、温哥华瘢痕量表、疼痛/瘙痒视觉模拟量表以及患者对瘢痕的主观满意度评估瘢痕分割研究和瘢痕质量。

结果

共有61例患者完成了研究。瘢痕宽度、温哥华瘢痕量表评分以及患者的主观满意度表明,弹性硅胶封闭片与更窄的瘢痕相关,且瘢痕外观有显著改善。两种方法在疼痛/瘙痒视觉模拟量表方面无显著差异。

结论

我们的研究结果表明,弹性硅胶封闭片是一种有效的瘢痕治疗方法,在传统开放性甲状腺切除术后可形成更窄且更好的瘢痕。传统开放性甲状腺切除术后使用弹性硅胶封闭片可能会在术后早期减少增生性瘢痕的形成。

试验注册

ChiCTR2100049740。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/07576424fa4c/13555_2022_763_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/0aff0fadd968/13555_2022_763_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/38d09861c5d1/13555_2022_763_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/0b499f690936/13555_2022_763_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/504d297aafdc/13555_2022_763_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/c845cf021338/13555_2022_763_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/07576424fa4c/13555_2022_763_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/0aff0fadd968/13555_2022_763_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/38d09861c5d1/13555_2022_763_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/0b499f690936/13555_2022_763_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/504d297aafdc/13555_2022_763_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/c845cf021338/13555_2022_763_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c698/9357594/07576424fa4c/13555_2022_763_Fig6_HTML.jpg

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