帕金森病患者认知障碍对其照顾者心理健康的影响：系统评价方案。

The impact of cognitive impairment of individuals with Parkinson's disease on their caregivers' mental health: A systematic review protocol.

机构信息

Department of Neuropsychology, Faculty of Social Sciences, Institute of Psychology, University of Gdansk, Gdansk, Poland.

Department of Clinical and Health Psychology, Faculty of Social Sciences, Institute of Psychology, University of Gdansk, Gdansk, Poland.

出版信息

PLoS One. 2022 Jul 19;17(7):e0271480. doi: 10.1371/journal.pone.0271480. eCollection 2022.

DOI:10.1371/journal.pone.0271480

PMID:35853013

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9295953/

Abstract

INTRODUCTION

Parkinson's disease is a motor disease, the second most common neurodegenerative disorder with cardinal symptoms including bradykinesia, rigidity, and rest tremor accompanied by cognitive difficulties. The caregivers play a crucial role for individuals with Parkinson's disease; however, many of them may suffer from high caregiver burden and mental health deterioration. This protocol of a systematic review presents a methodology of the review about the impact of cognitive impairment of individuals with Parkinson's disease on their caregivers' mental health.

MATERIAL AND METHODS

Research will be identified by combining electronic databases searching and hand searching. The following databases will be included: Medline, PsycInfo, Web of Sciences, Cochrane, CINAHL, Embase and Scopus. The inclusion and exclusion criteria followed to PECOS model. The population of informal caregivers is defined as family members providing care on a patient with Parkinson's disease. Exposure is linked with the evaluation of a cognitive functioning and outcome is defined as mental health among caregivers of individuals with Parkinson's disease. We will include two types of studies: observational and intervention. Both, screening and eligibility will be done by two independent reviewers. Study quality will be assessed by two authors independently. Data will be extracted by two reviewers independently and will follow a pre-pilot extraction form. Any discrepancies will be resolved by discussion or/and consultation with another reviewer. The synthesis without meta-analysis (SWiM) guidelines will be used to report on included studies data. The metanalysis with usage the statistical software R version 4.1.2 (2021-11-01) "Bird Hippie" and R metaphor package 3.0-2 of will be conducted if possible.

DISCUSSION

The goal of this systematic review is to present the association between caregivers' mental health problems and their proteges' cognitive impairment. It will enable to identify the gaps in literature and its methodology giving the suggestions for further research.

PROTOCOL REGISTRATION

Protocol registration number in PROSPERO: CRD42022296670.

摘要

简介

帕金森病是一种运动障碍疾病，是第二常见的神经退行性疾病，其主要症状包括运动迟缓、僵硬和静止性震颤，同时伴有认知困难。照顾者对帕金森病患者起着至关重要的作用；然而，他们中的许多人可能会承受着巨大的照顾者负担和心理健康恶化的压力。本系统评价方案介绍了一项关于帕金森病患者认知障碍对其照顾者心理健康影响的综述方法。

材料与方法

通过结合电子数据库搜索和手工搜索，将确定研究。将纳入以下数据库：Medline、PsycInfo、Web of Sciences、Cochrane、CINAHL、Embase 和 Scopus。遵循 PECOS 模型的纳入和排除标准。非正规照顾者的人群定义为为帕金森病患者提供照顾的家庭成员。暴露与认知功能评估相关，结局定义为帕金森病患者照顾者的心理健康。我们将纳入两种类型的研究：观察性研究和干预性研究。筛查和资格审查将由两名独立的评审员进行。两名作者将独立评估研究质量。数据将由两名评审员独立提取，并遵循预试验提取表。任何分歧将通过讨论或/和咨询另一名评审员解决。将使用无荟萃分析（SWiM）指南报告纳入研究的数据。如果可能，将使用 R 版本 4.1.2（2021-11-01）“Bird Hippie”和 R 隐喻包 3.0-2 的统计软件进行荟萃分析。