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2009-2020 年向英国国家毒物信息服务中心报告的外来蛇咬伤。

Bites by exotic snakes reported to the UK National Poisons Information Service 2009-2020.

机构信息

National Poisons Information Service Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland.

National Poisons Information Service Edinburgh, Edinburgh, United Kingdom of Great Britain and Northern Ireland.

出版信息

Clin Toxicol (Phila). 2022 Sep;60(9):1044-1050. doi: 10.1080/15563650.2022.2077748. Epub 2022 Jul 19.

DOI:10.1080/15563650.2022.2077748
PMID:35853475
Abstract

Snakebite is recognised as a neglected tropical disease and a cause of substantial morbidity and mortality. Whilst the most medically important snakes are typically native of Asia, Africa, Latin America and Oceania, the possibility of encountering these snakes is no longer limited by geography due to an increasing number of exotic (non-native) snakes being held in captivity. A retrospective review of snakebite enquiries to the UK National Poisons Information Service (NPIS) between 2009 and 2020. Enquiries about the European adder ( or where the identity of the snake was unknown were excluded. There were 321 exotic snakebites in 300 patients involving 68 different species during this period. Ten patients were bitten on more than one occasion. The majority of patients (64.5%) were male. Most bites were inflicted by snakes of the family Colubridae (184/321, 57.3%); seventeen bites resulted in moderate symptoms (predominantly swelling of the bitten limb). There were 30 (9.3%) bites by Viperidae and 14 (4.3%) bites by Elapidae. All severe cases ( = 15) resulted from bites by either Viperidae ( = 10) or Elapidae ( = 5). Antivenom was given in 17 cases. One fatality was recorded. Despite their low incidence, exotic snakebites present a substantial challenge for UK healthcare professionals. Although rare, these bites typically occur in individuals (usually male) who keep snakes as part of their occupation or hobby and are therefore at risk of multiple bites. Bites can result in venom hypersensitisation and the risk of venom-induced anaphylaxis. Rapid access to expert clinical advice is available in the UK on a 24-hour basis through the National Poisons Information Service and is strongly recommended in all cases of exotic snakebite.

摘要

蛇伤被认为是一种被忽视的热带病,也是导致大量发病率和死亡率的原因。虽然最具医学重要性的蛇类通常原产于亚洲、非洲、拉丁美洲和大洋洲,但由于越来越多的外来(非本地)蛇类被圈养,接触这些蛇类的可能性不再受地理限制。对英国国家毒物信息服务中心(NPIS)在 2009 年至 2020 年期间收到的蛇伤咨询进行回顾性分析。咨询中排除了关于欧洲蝰蛇(Vipera berus)的咨询,以及身份不明的蛇类的咨询。在此期间,有 300 名患者中的 321 例发生了 68 种不同物种的外来蛇伤。有 10 名患者被咬伤不止一次。大多数患者(64.5%)为男性。大多数咬伤是由 Colubridae 科的蛇类造成的(184/321,57.3%);17 例咬伤导致中度症状(主要是咬伤肢体肿胀)。有 30 例(9.3%)咬伤来自 Viperidae 科,14 例(4.3%)咬伤来自 Elapidae 科。所有严重病例( = 15)均由 Viperidae( = 10)或 Elapidae( = 5)咬伤引起。在 17 例中使用了抗蛇毒血清。记录了 1 例死亡。尽管发病率低,但外来蛇伤对英国医疗保健专业人员构成了重大挑战。尽管罕见,但这些咬伤通常发生在作为职业或爱好养蛇的个人(通常为男性)身上,因此有多次咬伤的风险。咬伤可导致毒液过敏和毒液诱导的过敏反应的风险。在英国,通过国家毒物信息服务中心,24 小时都可以获得专家临床建议,强烈建议所有外来蛇伤病例都应获得该建议。

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