Karampoor Sajad, Afrashteh Fatemeh, Rahmani Shahrzad, Laali Azadeh
Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran.
Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Respir Med Case Rep. 2022 Jul 14;38:101702. doi: 10.1016/j.rmcr.2022.101702. eCollection 2022.
COVID-19 can damage the endothelial cells of every organ in the body and lead to vasculopathy and vasculitis. It has been shown that various types of vasculitis could be a new manifestation of COVID-19. Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic necrotizing vasculitis that affects small vessels. Here we report our experience with a 42-year-old man with a 3-weeks history of fever of unknown origin after two months from COVID-19 recovery presented with loss of appetite, loss of weight, and paresthesia in his lower extremities. After required evaluations including nerve biopsy, EGPA was diagnosed for him.
新型冠状病毒肺炎(COVID-19)可损害人体各个器官的内皮细胞,导致血管病变和血管炎。研究表明,各种类型的血管炎可能是COVID-19的一种新表现形式。嗜酸性肉芽肿性多血管炎(EGPA)是一种罕见的累及小血管的系统性坏死性血管炎。在此,我们报告一名42岁男性的病例,该患者在COVID-19康复两个月后出现不明原因发热3周,伴有食欲不振、体重减轻和下肢感觉异常。经过包括神经活检在内的必要评估后,确诊为EGPA。