Zhang Yi, Ren Yubin, Liu Yangyi, Wang Fan, Zhang Hongjie, Liu Kai
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China.
Department of Chemistry, Tsinghua University, Beijing, 100084, P. R. China.
Chempluschem. 2022 Jul 4;87(9):e202200183. doi: 10.1002/cplu.202200183.
The exponential growth of the total amount of global data presents a huge challenge to mainstream storage media. The emergence of molecular digital storage inspires the development of the new-generation higher-density digital data storage. In particular, DNA with high storage density, reproducibility, and long recoverable lifetime behaves the ideal representative of molecular digital storage media. With the development of DNA synthesis and sequencing technologies and the reduction of cost, DNA digital storage has attracted more and more attention and achieved significant breakthroughs. Herein, this Review briefly describes the workflow of DNA storage, and highlights the storage step of DNA digital data storage. Then, according to different information storage forms, the current DNA information encryption methods are emphatically expounded. Finally, the brief perspectives on the current challenges and optimizing proposals in DNA information preservation and encryption are presented.
全球数据总量的指数级增长对主流存储介质提出了巨大挑战。分子数字存储的出现推动了新一代高密度数字数据存储的发展。特别是，具有高存储密度、可重复性和长可恢复寿命的DNA是分子数字存储介质的理想代表。随着DNA合成和测序技术的发展以及成本的降低，DNA数字存储越来越受到关注并取得了重大突破。在此，本综述简要描述了DNA存储的工作流程，并重点介绍了DNA数字数据存储的存储步骤。然后，根据不同的信息存储形式，着重阐述了当前的DNA信息加密方法。最后，对DNA信息保存和加密中的当前挑战及优化建议给出了简要展望。
