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为 CyberKnife M6 型医用直线加速器治疗计划系统进行调试和验证

Commissioning and validation of RayStation treatment planning system for CyberKnife M6.

机构信息

Institute of Radiation Physics, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.

Radio-Oncology Department, Lausanne University Hospital and Lausanne University, Lausanne, Switzerland.

出版信息

J Appl Clin Med Phys. 2022 Aug;23(8):e13732. doi: 10.1002/acm2.13732. Epub 2022 Jul 20.

Abstract

BACKGROUND

RaySearch (AB, Stockholm) has released a module for CyberKnife (CK) planning within its RayStation (RS) treatment planning system (TPS).

PURPOSE

To create and validate beam models of fixed, Iris, and multileaf collimators (MLC) of the CK M6 for Monte Carlo (MC) and collapsed cone (CC) algorithms in the RS TPS.

METHODS

Measurements needed for the creation of the beam models were performed in a water tank with a stereotactic PTW 60018 diode. Both CC and MC models were optimized in RS by minimizing the differences between the measured and computed profiles and percentage depth doses. The models were then validated by comparing dose from the plans created in RS with both single and multiple beams in different phantom conditions with the corresponding measured dose. Irregular field shapes and off-axis beams were also tested for the MLC. Validation measurements were performed using an A1SL ionization chamber, EBT3 Gafchromic films, and a PTW 1000 SRS detector. Finally, patient-specific QAs with gamma criteria of 3%/1 mm were performed for each model.

RESULTS

The models were created in a straightforward manner with efficient tools available in RS. The differences between computed and measured doses were within ±1% for most of the configurations tested and reached a maximum of 3.2% for measurements at a depth of 19.5-cm. With respect to all collimators and algorithms, the maximum averaged dose difference was 0.8% when considering absolute dose measurements on the central axis. The patient-specific QAs led to a mean result of 98% of points fulfilling gamma criteria.

CONCLUSIONS

We created both CC and MC models for fixed, Iris, and MLC collimators in RS. The dose differences for all collimators and algorithms were within ±1%, except for depths larger than 9 cm. This allowed us to validate both models for clinical use.

摘要

背景

RaySearch(AB,斯德哥尔摩)在其 RayStation(RS)治疗计划系统(TPS)中发布了一个用于 CyberKnife(CK)计划的模块。

目的

为 RS TPS 中的 Monte Carlo(MC)和崩溃锥形束(CC)算法创建并验证 CK M6 的固定、虹膜和多叶准直器(MLC)的束模型。

方法

在水箱中使用立体定向 PTW 60018 二极管进行了创建束模型所需的测量。通过最小化测量和计算轮廓之间的差异以及百分深度剂量来优化 CC 和 MC 模型。然后通过将 RS 中创建的计划的剂量与不同 phantom 条件下的单个和多个光束的相应测量剂量进行比较来验证模型。还对 MLC 进行了不规则场形状和离轴光束的测试。验证测量使用 A1SL 电离室、EBT3 Gafchromic 胶片和 PTW 1000 SRS 探测器进行。最后,对每个模型进行了具有 3%/1 mm 伽马标准的患者特定 QA。

结果

模型以 RS 中可用的高效工具以直接的方式创建。在大多数测试配置中,计算剂量与测量剂量之间的差异在±1%以内,在 19.5 厘米深度的测量中达到最大 3.2%。对于所有准直器和算法,考虑中央轴上的绝对剂量测量时,最大平均剂量差异为 0.8%。患者特定 QA 的结果为 98%的点符合伽马标准。

结论

我们在 RS 中为固定、虹膜和 MLC 准直器创建了 CC 和 MC 模型。除了深度大于 9 厘米的情况外,所有准直器和算法的剂量差异都在±1%以内。这使我们能够验证这两种模型的临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8acb/9359029/7a8faa28621f/ACM2-23-e13732-g001.jpg

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