新冠病毒疫苗接种后暴发性视神经脊髓炎谱系疾病（NMOSD）：是否需要重新考虑？
Fulminant neuromyelitis optica spectrum disorder (NMOSD) following COVID-19 vaccination: A need for reconsideration?
机构信息
Center for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Center for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Mult Scler Relat Disord. 2022 Oct;66:104035. doi: 10.1016/j.msard.2022.104035. Epub 2022 Jul 5.
During the coronavirus disease 2019 (COVID-19) pandemic, mass vaccination was a beneficial strategy in many countries. Nevertheless, reports of serious complications such as postvaccination neuromyelitis optica spectrum disorder (NMOSD) raised concerns about the safety of vaccines. Anamnart and colleagues explained postvaccination NMOSD following different vaccines, including COVID-19. To emphasize the message of this article, in this letter, we present a unique case of postvaccination NMOSD with a fulminant and fatal course, which may show a plausible relationship between COVID-19 vaccination and triggering anti-aquaporin-4 antibody (AQP4-Ab).
在 2019 冠状病毒病（COVID-19）大流行期间，大规模接种疫苗是许多国家的一项有益策略。然而，接种疫苗后出现严重并发症（如视神经脊髓炎谱系障碍（NMOSD））的报告引起了对疫苗安全性的关注。Anamnart 及其同事解释了不同疫苗（包括 COVID-19 疫苗）接种后的 NMOSD。为了强调本文的信息，在这封信中，我们报告了一例 COVID-19 疫苗接种后出现暴发性和致命性 NMOSD 的独特病例，这可能表明 COVID-19 疫苗接种与触发抗水通道蛋白-4 抗体（AQP4-Ab）之间存在合理的关系。
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