Riad-Fahmy D, Read G F, Walker R F, Walker S M, Griffiths K
J Reprod Med. 1987 Apr;32(4):254-72.
Assessment of ovarian activity based on saliva samples has proven particularly useful in studies of women in well-developed countries and is potentially of even greater value in women of lower socioeconomic status in Third World countries. Assay techniques suitable for measuring low concentrations of steroids in saliva have become available only recently, so data derived from salivary sampling regimens are far less extensive than those based on plasma or urinary sampling procedures. Collecting saliva is an attractive alternative to the more conventional procedures because of the ease of frequent collection and freedom from religious and social constraints. Simple, direct assays for salivary progesterone have been established, but those for estradiol require considerably more research before becoming useful in routine practice. Predicting ovulation with data derived from saliva sampling awaits the development of more suitable assays for salivary estradiol.
基于唾液样本评估卵巢活动已被证明在发达国家女性的研究中特别有用，而在第三世界国家社会经济地位较低的女性中可能具有更大的价值。适合测量唾液中低浓度类固醇的检测技术直到最近才出现，因此来自唾液采样方案的数据远不如基于血浆或尿液采样程序的数据广泛。由于易于频繁采集且不受宗教和社会限制，收集唾液是比传统程序更具吸引力的替代方法。已经建立了简单、直接的唾液孕酮检测方法，但雌二醇检测方法在常规应用中发挥作用之前还需要进行大量研究。利用唾液采样数据预测排卵有待开发出更适合的唾液雌二醇检测方法。
