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献血者中乙型肝炎、丙型肝炎和人类免疫缺陷病毒的感染率

Frequency of Hepatitis B, C, and Human Immunodeficiency Virus in Blood Donors.

作者信息

Ahmed Rehana, Fatima Mushkbar, Ashfaq Javeria, Tariq Syeda Faryal, Naseer Imran, Asif Muhammad, Borhany Munira

机构信息

Department of Hematology, National Institute of Blood Diseases and Bone Marrow Transplant, Karachi, PAK.

Department of Research and Development, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, PAK.

出版信息

Cureus. 2022 Jun 15;14(6):e25978. doi: 10.7759/cureus.25978. eCollection 2022 Jun.

Abstract

INTRODUCTION

Blood donation is considered an important source of infection transmitted through transfusion, especially in developing countries like Pakistan.

OBJECTIVE

To find out the frequency of seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) among blood donors in the blood bank.

METHODS

A prospective cohort study was carried out on blood donors at the National Institute of Blood Disease and Bone Marrow Transplant, Karachi, during the period of January 1, 2019 to December 31, 2020. The descriptive statistical analysis to find out the percentages and frequencies was implemented using SPSS version 23 (IBM Corp., Armonk, NY).

RESULTS

During the study duration, a total of 23,656 blood donors visited and donated blood, including 12,234 blood donors in the year 2019 and 11,422 blood donors in the year 2020. According to the analysis, only 1.4% of patients with HBV, 1.5% with HCV, and 0.03% were seropositive in the year 2020. In 2019, 1.6% HBV, 2.07% HCV, and 0.09% HIV blood donors were seropositive with a significant 0.00 -value.

CONCLUSION

It is concluded that hepatitis C is the most commonly occurring in donors compared to HBV and HIV. HBV vaccines are available in Pakistan, which is why cases are fewer than HCV.

摘要

引言

献血被认为是输血传播感染的一个重要来源,尤其是在巴基斯坦等发展中国家。

目的

了解血库中献血者感染乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和人类免疫缺陷病毒(HIV)的血清流行率。

方法

于2019年1月1日至2020年12月31日期间,在卡拉奇国家血液疾病和骨髓移植研究所对献血者进行了一项前瞻性队列研究。使用SPSS 23版(IBM公司,纽约州阿蒙克)进行描述性统计分析以得出百分比和频率。

结果

在研究期间,共有23656名献血者前来献血,其中2019年有12234名献血者,2020年有11422名献血者。根据分析,2020年只有1.4%的HBV患者、1.5%的HCV患者和0.03%呈血清阳性。2019年,1.6%的HBV、2.07%的HCV和0.09%的HIV献血者呈血清阳性,p值具有显著性。

结论

得出的结论是,与HBV和HIV相比,丙型肝炎在献血者中最为常见。巴基斯坦有HBV疫苗,这就是HBV病例比HCV少的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1e1/9287592/3709476b5938/cureus-0014-00000025978-i01.jpg

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