Miratashi Yazdi Seyed Amir, Nazar Elham
Department of General Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Department of Pathology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ann Med Surg (Lond). 2022 Jun 28;79:104109. doi: 10.1016/j.amsu.2022.104109. eCollection 2022 Jul.
Castleman's disease (CD) is an unusual nonmalignant lymphoproliferative disorder which presented with enlarged hyperplastic lymphoid tissue and had three subtypes, hyaline-vascular, plasma cell, and mixed form according to histologic findings.
We report a 31-year-old woman who presented with abdominal pain from 3 months ago. Imaging studies showed a well-defined mass on back of pancreas without any invasion. The histopathological examination revealed lymphoid tissue with prominent vascular proliferation and hyalinization of the vessel walls compatible with Hyaline vascular CD. So, pathological assessment is essential for the diagnosis.
Unicentric CD must be considered as differential diagnosis in a solid solitary abdominal mass. In patients with abdominal mass of an ambiguous nature, surgical resection is necessary as diagnostic tool and the first treatment approach.
卡斯特曼病(CD)是一种罕见的非恶性淋巴增生性疾病,表现为增生的淋巴组织肿大,根据组织学表现可分为透明血管型、浆细胞型和混合型三种亚型。
我们报告一名31岁女性,她3个月前开始出现腹痛。影像学检查显示胰腺后方有一个边界清晰的肿块,无任何浸润。组织病理学检查显示淋巴组织伴有明显的血管增生和血管壁透明变性,符合透明血管型卡斯特曼病。因此,病理评估对诊断至关重要。
单中心性卡斯特曼病必须被视为实性孤立性腹部肿块的鉴别诊断。对于性质不明的腹部肿块患者,手术切除作为诊断工具和首要治疗方法是必要的。